Uses of Navelbine

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1. What is Navelbine?

Navelbine medicine contains the active ingredient Vinorelbine (as Vinorelbine ditartrate) 20mg along with other excipients. In which, Vinorelbine is known as a drug belonging to the Vinca Alkaloid group.
The main use is this ingredient in cancer treatment, especially for metastatic breast cancer and lung cancer. The mechanism of action of the drug is to interact with Tubulin - an important component of microtubules. Since then, the drug changes the shape of microtubules, reduces the ability to maintain cell structure, and blocks some processes of transporting endogenous substances, inhibits mitosis, and prevents cell division. Therefore, the tumor cannot grow, reducing the negative effects on the patient's body.

2. Uses of Navelbine

Thanks to its main ingredient, Vinorelbine, Navelbine is clinically prescribed for patients with non-small cell lung cancer and metastatic breast cancer.
Besides the uses of the drug, Navelbine is contraindicated for patients with the following conditions:
Allergy to any ingredient of the drug Patients with severe liver failure.

3. Dosage and usage of Navelbine

3.1. Navelbine is used orally. To minimize stomach pain as well as achieve the most effective treatment, patients should take the drug after eating.
When taking the medicine, swallow the tablet whole, do not chew or break the medicine and drink with plenty of water.
3.2. Dosage This is a prescription drug, so patients need to take it according to the dose prescribed by the doctor. Never change the dose or stop taking the medicine without consulting your doctor. Patients can refer to the manufacturer's recommended dosage:
First cycle: 60 mg/m2. Subsequent cycles are 60-80 mg/m2. Dosage for cancer patients with kidney failure will be reduced.

4. Navelbine side effects

Navelbine drug causes side effects during treatment. The most common side effects can be followed by nausea, vomiting, shortness of breath or angina, anemia ... Some side effects are rarer in patients treated. with Navelbine is to reduce tendon reflexes, limb weakness,...
When these signs appear, the patient should notify the doctor to receive advice and timely treatment measures.

5. Navelbine drug interactions

There have been reports of drug interactions between Navelbine and some other drugs such as anticoagulants or Phenytoin... As a result of this situation, the pharmacological properties of the drug itself or other drugs used together are impaired. change.
Therefore, to avoid drug interactions, patients should provide a list of all medications they are taking (including prescription, nonprescription, herbal and dietary supplements) and show it to their doctor or pharmacist. and consulting.

6. Be careful when using Navelbine

During treatment with Navelbine, it is necessary to regularly monitor the patient's body functions. Always closely monitor hematological problems. Patients with impaired liver and kidney function should be cautious when using the drug. The use of underdosage or overdose makes the drug not achieve the highest therapeutic effect, even causing side effects. Therefore, patients need to comply with the dosage instructions from the primary treating doctor. Women who are pregnant, especially in the first 3 months of pregnancy, should only use the drug when prescribed by a doctor because this drug will significantly affect the fetus. Lactating women may be advised to discontinue breast-feeding prior to treatment with Navelbine. Before using, check the expiry date of the medicine. When not in use, the drug should be collected and disposed of according to the instructions of the manufacturer or those in charge of the medical field. Store the medicine in a dry place, avoid direct exposure to sunlight or high temperature, it can convert the ingredients in the medicine.

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