Uses of Glotizine

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1. What is Glotizine?

Glotizine 10mg drug has the main ingredient Cetirizine hydrochloride 10mg and other excipients. The drug is prepared in the form of film-coated tablets and is used for the symptomatic treatment of allergic manifestations such as:
Seasonal allergic rhinitis or perennial allergic rhinitis; Allergic conjunctivitis ; Chronic urticaria; Skin diseases that cause itching due to allergies. >>> See more: Note when using antihistamines H1 in the treatment of allergies

2. Instructions on how to take Glotizine

Glotizine 10mg should be used as directed by a doctor or patients can refer to the dosage below:
Children > 6 years old and adults: Take the usual dose - 1 Glotizine 10mg tablet / time; Patients with impaired liver function: No dose adjustment is required, except in case of liver failure combined with moderate and severe renal impairment, dose adjustment is required; Patients with impaired renal function: Dosage will be adjusted by the doctor according to the response of renal function. Specifically: Creatinine clearance Clcr ≥ 80ml/min: Take 1 tablet/time/day; Creatinine clearance Clcr 50 - 79ml/min: Take the same dose as normal people; Creatinine clearance Clcr 30 - 49ml/min: Take 5mg/time/day; Creatinine clearance Clcr 11 - 49ml/min: Take 5mg/time/2 days; End stage renal failure or dialysis (< 10ml/min): Not allowed. How to use: Take orally, during or outside of meals with a sufficient amount of water.

3. Glotizine side effects

In some cases, Glotizine 10mg may still cause some adverse effects such as:
Common: Mild gastrointestinal disorders, dizziness, drowsiness (drowsiness), dry mouth, fatigue , nausea; Uncommon: Flushing, increased salivation, anorexia or increased appetite, urinary retention; Rare: Severe hypotension, anaphylaxis, hepatitis, cholestasis, glomerulonephritis, hemolytic anemia, thrombocytopenia. If you see any of the above side effects, the patient should immediately notify a qualified doctor or pharmacist for timely assistance.

4. Note when using Glotizine

Before using Glotizine in treatment, users should pay special attention to the following notes:
Do not use the drug for people who need to concentrate when working, driving or operating machinery; Avoid taking Cetirizine with alcohol or other CNS depressants, as it may decrease alertness; Dosage reduction is required in the elderly; Dosage adjustment is required in patients with hepatic or renal impairment. In addition, the use of Glotizine is contraindicated in the following cases:
Hypersensitivity to any component of the drug or to hydroxyzin; Patients with end-stage renal failure. The formula contains Lactose, so Glotizine should not be used for patients with poor glucose-Galactose intolerance, hereditary galactose intolerance, Lactase enzyme deficiency; Do not use this medicine for pregnant women; The drug should not be used by women who are breastfeeding because cetirizine is excreted in milk.

5. Glotizine drug interactions

To avoid unwanted interactions, do not use Glotizine in combination with:
Bronchodilator Theophyllin 400mg: This drug may reduce the clearance of Cetirizine; Alcohol and neuroleptic drugs: Increases drowsiness, reduces alertness, and is dangerous when doing tasks that require concentration. In general, Glotizine has the advantage of quickly reducing symptoms caused by allergic rhinitis. The drug is cheap, in pill form, so it is easy to carry and convenient to use. Besides the advantages, the drug still has some limitations such as: not for patients with end-stage renal failure, pregnant and lactating women.
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