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Verarem medicine has the main active ingredient is Verapamil hydrochloride with a concentration of 40mg and other excipients in sufficient quantities. The drug is prepared in the form of sugar coated tablets, suitable for direct oral administration. Verarem is used in the treatment of angina, arrhythmias, and hypertension.1. What is Verarem?
What is Verarem? Verarem medicine has the main active ingredient is Verapamil hydrochloride with a concentration of 40mg and other excipients in sufficient quantities. The drug is prepared in the form of sugar coated tablets, suitable for direct oral administration. Verarem drug is used in the treatment of angina pectoris , treatment of arrhythmias , hypertension .
Packing is a box of 5 blisters, each blister contains 10 tablets.
1.1. Pharmacodynamics of active ingredient Verapamil hydrochloride: The main active ingredient Verapamil is a calcium channel blocker with antiarrhythmic, angina, and antihypertensive effects.
1.2. Pharmacokinetics of the active ingredient Verapamil hydrochloride Absorption: Over 90% of an oral dose is absorbed, bioavailability is about 20-35% because of first-pass metabolism by the liver, if the drug is used for a prolonged period or at an increased dose. use, bioavailability may be increased. When administered intravenously the drug is metabolized very quickly. When infusion in humans, the drug is eliminated through 2 phases. The drug begins to work 1 to 2 hours after oral administration and within 1-5 minutes when administered intravenously. Distribution: The drug is highly bound to plasma proteins approximately 90%. Metabolism: The drug is metabolized mainly in the liver in the form of conjugates. Elimination ability: The main active substance is eliminated by the kidneys, in the form of conjugated and unmetabolized metabolites, excreted in the bile and feces. 1.3. The action of active ingredient Verapamil hydrochloride Active ingredient Verapamil is a calcium channel blocker, blocking the Ca ++ current through the channel, slowing down the transmission of neurons and cardiomyocytes (antiarrhythmic effect) and into muscle cells smooth vascular wall with vasodilator effect. In the treatment of coronary insufficiency, active ingredient Verapamil reduces myocardial oxygen consumption directly by interfering with myocardial oxygen-consuming metabolism and indirectly by reducing afterload. Active ingredient Verapamil increases coronary blood flow and prevents coronary artery spasm. Active ingredient Verapamil has strong antiarrhythmic effects, especially for supraventricular arrhythmias. The drug prolongs impulse conduction in the atrioventricular node, so depending on the type of tachyarrhythmia, restores sinus rhythm or slows the ventricular rate.
2. What disease does Verarem treat?
Verarem 40 is most commonly used in the treatment of hypertension, stable or unstable angina, paroxysmal supraventricular tachycardia.Users should use the drug regularly according to the instructions of the treating doctor, and at the same time, it should be combined with a healthy, scientific diet, eating less foods containing a lot of fat, cholesterol, increasing cholesterol. Add more vegetables and fruits. Absolutely do not use stimulants such as alcohol, tobacco or drugs.
Limit staying up late after 11pm, get enough sleep every day and exercise regularly to keep your body healthy.
3. Usage and dosage of Verarem
3.1. How to use Verarem Drug Verarem is prepared in the form of sugar coated tablets, suitable for direct oral use.
3.2. How to use Verarem medicine Verarem drug has a dose recommended by doctors as follows:
Dosage for angina for adults is 120mg divided into 3 times a day. Dosage for supraventricular tachycardia in adults: the usual dose is 40-120mg of the drug divided into 3 times a day. Dosage for children: the usual dose is 40-120mg of the drug 2-3 times a day for children over 2 years old. Dosage for treatment of high blood pressure for adults is 120mg - 160mg per day divided into 2 times a day. It should be noted: The above drug dosage is only for reference, patients with symptoms of the disease need to go to medical centers for examination. After the diagnosis process, the doctor will determine the pathology and give a reasonable treatment and prescription, as well as an effective diet.
4. In case of over/forgotten dose of Verarem
In case of Verarem overdose: The symptoms users may experience when overdosing on Verarem 40 include hypotension, sinus bradycardia, shock, second-degree or second-degree atrioventricular block, and total atrioventricular block. ,... It is necessary to avoid overuse of the drug, if the user accidentally takes an overdose, the user should go to the hospital for timely emergency care. In case of missed dose of Verarem: Users need to use the drug fully and at the right time. Strict adherence to the medication regimen will help ensure the effectiveness of the treatment process. In the event of a missed dose, the user can skip the missed dose and take the next dose. Do not take a double dose to make up for the missed dose.
5. Undesirable effects of the drug Verarem
When using Verarem 40, users may experience some unwanted effects, such as itchy rashes, pimples, allergies, skin redness, rashes, urticaria, even reactive reactions. guard. If the user experiences the above symptoms or any other abnormality when taking the drug, it is necessary to notify the treating doctor for advice on reducing the dose, stopping the use of the drug in case of necessity. The above is not exhaustive to all side effects and others that may occur. You need to pay attention to proactively notify your treating doctor for medical advice about adverse effects when using Verarem.
6. Verarem . drug interactions
Interactions of Verarem drugs that may occur during use are as follows:
Drugs that can interact with Verarem drugs. Verarem drug interactions may change its ability to work or increase the effect of unwanted effects. It is important that you proactively list all of the prescription and over-the-counter medicines, herbal products, or health foods you are taking to your treating physician or clinical pharmacist. used to minimize the types of interactions that may cause unwanted effects on the user's health. Verarem drug interactions with food and drinks: When using this drug with foods or alcohol, beer, tobacco... because in those foods and beverages containing other active ingredients, there should be other active ingredients. may cause antagonism or synergistic effects with the drug. You need to actively read the instructions for use of the drug or consult your doctor about how to use Verarem with food, alcohol and tobacco.
7. Some notes when using Verarem
In the process of using Verarem, patients should pay attention to the following issues:
7.1. Contraindications of the drug Verarem Verarem drug is not used in the following cases:
Shock due to cardiovascular problems, complicated acute myocardial infarction, 2nd or 3rd degree atrioventricular block, sinus block- atrial fibrillation, sinus node insufficiency syndrome. Patients with decompensated heart failure, hypotension, atrial fibrillation or flutter with Wolf-Parkinson-White syndrome, also known as pre-excitation syndrome, ventricular tachycardia, hypotension. People with a history of allergy to the main active ingredient Verapamil. Do not take drugs containing the active ingredient Verapamil intravenously with a beta-adrenergic blocker. It should be noted: Because this is a cardiovascular drug, contraindications must be understood as absolute contraindications, that is, no reason, or in any emergency, that contraindication can change. to take medicine.
7.2. Attention and caution when using Verarem 40 Note and caution when using Verarem 40 in the following cases:
Caution when using Verarem for people with severe liver or kidney failure, tall people age over 65 years old. Pregnant women or women who are breastfeeding can use the drug, but it is necessary to consult a doctor to treat the disease. Verarem 40 can be used by drivers and machine operators. This is because it does not cause drowsiness or loss of concentration. Store Verarem in a dry place, at a temperature of 15-30 degrees Celsius in tightly closed containers, away from moisture and away from direct light. In addition, it is necessary to store Verarem medicine out of the reach of children and family pets. Absolutely do not use Verarem when it has expired, watery, distorted, or shows signs of metamorphosis. Consult environmental protection companies for how to dispose of drugs. Absolutely do not flush the medicine down the toilet or plumbing.
In short, Verarem drug has the main active ingredient, Verapamil hydrochloride, with a strength of 40mg. Verarem is used in the treatment of angina, arrhythmias, and hypertension. When prescribed by a doctor, patients should carefully read the instructions for use, consult the treating doctor/clinical pharmacist before using the drug. Absolutely do not arbitrarily buy Verarem to treat the disease at home, because there may be unwanted side effects on health.
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