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Dutasteride 5a drug has the main ingredient is Dutasteride, used in the treatment of diseases of the urinary tract. Please refer to this article to get more useful information about this drug.
1. Uses of Dutasteride 5A
Dutasteride is a testosterone-5-alpha-reductase inhibitor that reduces the production of dihydrotestosterone (DHT), an androgenic sex hormone. Dutasteride can reduce blood levels of DHT by up to 98%. Dutasteride 5a is indicated for the treatment and prevention of benign prostatic hypertrophy through the mechanism of reducing symptoms of the disease, reducing prostate size, improving urine circulation and reducing the risk of acute urinary retention. , the need for surgery related to benign prostatic hypertrophy.In addition, it is also combined with tamsulosin (alpha blocker) to treat and prevent the progression of benign prostatic hypertrophy.
On the other hand, absolutely do not use Dutasteride 5a in the following cases:
Patients who are allergic to any of the ingredients. Patients with a history of or are suffering from prostate cancer Patients with a history or disease. on liver Pregnant and breastfeeding women, limit use in young children.
2. Dosage and usage
During treatment with Dutasteride 5A, you need to absolutely follow your doctor's instructions. Do not arbitrarily increase or decrease the dose of the drug, change the method of taking it, do not give this medicine to others, even if they have the same symptoms as you.
Patients may be advised to take after meals or during meals. Swallow the tablet whole with water, do not chew or crush. Do not drink with other liquid solutions such as juice, tea, tea, alcohol, ... because it is likely to cause drug interactions. The minimum duration of treatment is 6 months to be able to objectively assess the response to treatment or not.
The recommended dose of Dutasteride 5a for adults is 1 tablet per day. Patients with renal impairment : No dose adjustment of Dutasteride 5A is required . Patients with hepatic impairment: There have been no studies on the effect of hepatic impairment on the pharmacokinetics of Dutasteride 5A. If you miss a dose, take another dose as soon as you remember. If it is almost time for your next dose, skip it and take your next dose as scheduled. Do not take 2 doses at the same time to make up for a missed dose.
Studies in volunteers have shown that doses up to 40 mg/day (80 times the therapeutic dose) for 1 week have shown no safety concerns. In clinical studies, when patients were given 5 mg/day for 6 months continuously for 6 months, no additional adverse effects other than those seen at 0.5 mg/day were observed. In case of overdose, monitor your own health and immediately contact the nearest emergency center for treatment. Currently, there is no specific antidote for Dutasteride 5a. Treatment includes symptomatic and supportive treatment.
5. Undesirable effects of Dutasteride 5A
During the use of Dutasteride 5A, you may experience the following undesirable effects:
Reproductive system and breasts: decreased libido, impotence, decreased sperm count and quality, breast abnormalities in men include enlarged breasts and breast pain (due to testosterone disorders), pain and swelling of the testicles, etc. These side effects may continue after treatment is stopped. Immune system: allergic reaction with manifestations of rash, hives, itching, urticaria, swelling of the throat, lips and tongue, ... Immediately contact the nearest emergency center for timely treatment. Psychiatric: depression, ... Other symptoms: hair loss, hyperpigmentation, ...
6. Drug interactions
Drug interactions can increase or decrease the effect of drugs. To avoid drug interactions, list all medications you are taking, including prescription and non-prescription drugs, vitamins, supplements, herbs, etc., and report it to your doctor. treatment. Do not start a new medication without consulting your doctor. The following drugs may interact with :
Isoniazid (anti-TB drug) Conivaptan (Vaprisol) Imatinib (Gleevec) Nefazodone (antidepressant) Antibiotics: clarithromycin, erythromycin, telitromycin, ... Antifungal drugs: itraconazole, ketoconazole, miconazole, voriconazole, ... Cardiovascular drugs: nicardipine, quinidine HIV/AIDS drugs: atazanavir, delavirdine, indinavir, nelfinavir, saquinavir, ritonavir.
7. Some notes when using Dutasteride 5A
Pregnant women absolutely do not use Dutasteride 5A drug, because it increases the risk of miscarriage, male genital malformations if the mother uses this drug during pregnancy. Pregnant women should limit their exposure to this drug. If there is contact with the drug, wash it off and notify the doctor immediately for timely instructions. There are no data on whether Dutasteride 5a is excreted in human milk. Therefore, do not take Dutasteride 5a while breastfeeding. Use of Dutasteride 5a does not affect the ability to drive and use machines. Do not participate in blood donation while taking Dutasteride 5a . Stopping the drug before 6 months to ensure it is safe to donate blood. Do not use alcohol and alcoholic beverages during treatment with Dutasteride 5a because it can cause drug interactions and cause side effects.
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