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Farizol belongs to the group of antiparasitic, anti-infective, anti-viral, anti-fungal drugs. Let's learn about the uses and notes when using Farizol through the article below.1. What is Farizol?
Farizol medicine contains the active ingredient Cefprozil in the form of Cefprozil monohydrate and excipients just enough for 1 tablet. The drug is prepared for users in the form of film-coated tablets and is packaged in boxes of 1 blister x 10 tablets with 2 types in different dosages including Farizol 250 and Farizol 500.
2. Uses of the drug Farizol
Farizol is a prescription medicine for the treatment of mild to moderate infections caused by strains of bacteria including:
Upper respiratory tract infections such as:
Pharyngitis, tonsillitis caused by St. pyogenes Otitis media and acute sinusitis caused by St. pneumoniae, H. influenza and Moraxella, catarrhalis. Lower respiratory tract infections:
People with secondary infection in case of acute bronchitis or exacerbation of chronic bronchitis caused by St. pneumoniae, H. influenza, and Moraxella, Catarrhalis. Skin and Structures: People with uncomplicated skin and structural infections caused by St. pyogenes or St. aureus including penicillinase-producing strains.
3. Dosage and how to use Farizol
How to use: The drug is prepared in the form of film-coated tablets that should be used orally. When drinking, do not chew the medicine, but drink the whole tablet with boiled water to cool.
Recommended dosage when using Farizol 250 and Farizol 500 for people 13 years of age and older are as follows:
People with sore throat or tonsillitis: Take 500mg once a day, maintain the drug for 10 days. Patients with moderate to severe acute sinusitis may require higher doses: 250mg or 500mg twice daily for 10 days. People with secondary infection in case of acute bronchitis or exacerbation of chronic bronchitis: Take 500mg twice a day for 10 days. Patients with uncomplicated skin and structural inflammation: Take 250mg/day 2 times or 500mg/day 1 or 2 times, within 10 days. Treating people with infections caused by St. pyogenes, the minimum duration of dosing is 10 days. Patients with hepatic impairment: No dosage adjustment is required. Patients with renal impairment, creatinine clearance 30-120 ml/min: Use the same dose as normal people. Patients with renal failure with creatinine clearance 0 - 29ml/min: Use 50% of the standard dose, treatment time for 10 days. Note: Because cefprozil is partially eliminated from the body during hemodialysis, it is necessary to give it to patients immediately after dialysis.
Management of missed dose:
If you miss a dose, you can take it within 1-2 hours compared to the indicated in the prescription. However, if the time is too far from the time when you need to take the medicine, you should not make up or double the dose, but proceed to take the next dose as indicated. It is important to follow the correct prescription or consult your doctor before deciding to change the dose. Overdose and treatment:
Manifestations of drug overdose are relatively similar to the appearance of side effects. Proven results when a single dose of 5000 mg/kg orally in rats or mice did not cause death or signs of toxicity. After a single dose of 3000 mg/kg, diarrhea and decreased appetite were observed in monkeys but not fatal. In addition, patients may experience liver and kidney toxicity because Cefprozil is eliminated mainly by the kidneys. In some cases of severe poisoning, which often occurs in patients with kidney disease, dialysis can be used to remove cefprozil from the body. Patients should be closely monitored for skin, facial, blood pressure.
4. Farizol side effects
Common side effects of Cefprozil are similar to those of other oral cephalosporin antibiotics. Approximately 2% of patients discontinued cefprozil therapy due to adverse events.
Common side effects when taking Farizol include:
Gastrointestinal tract: Occurrence of diarrhea, nausea or vomiting and abdominal pain. Hepatobiliary: Increased liver enzymes, alkaline phosphatase and bilirubin. In rare cases, jaundice may appear. Hypersensitivity: Rash, urticaria often occurs in children. Nervous: Dizziness, headache, insomnia and possible hyperactivity. Blood: Decreased white blood cells and eosinophils. Renal: Increased BUN, plasma creatinine. Symptoms of superinfection or genital itching and vaginitis appear. Other rare adverse events reported post-marketing include: anaphylaxis, angioedema, erythema multiforme or fever, reactions similar to Stevens-Johnson syndrome and thrombocytopenia.
During the course of using the drug, if the patient shows signs of the above-mentioned side effects or other unusual symptoms, it is necessary to stop the drug and go to the nearest medical center for advice. of a medical professional.
5. Farizol drug interactions
During the use of the drug, there may be an interaction between the drug Farizol with food or other drugs and functional foods, affecting the absorption, distribution, and metabolic rate of the drug, such as: The following:
Concomitant use of Aminoglycoside antibiotics with Cephalosporins can cause nephrotoxicity. The AUC of Cefprozil is doubled when co-administered with Probenecid. Cefprozil may cause false positives in urine sugar tests with Fehling or Benedict reagents and affect the results of the Clinistix enzyme test. A false-negative reaction to the Ferricyanide test to check blood sugar can occur. However, when using the alkaline picrate method, cefprozil did not affect the amount of creatinine in blood or urine. Note: In order to avoid adverse drug interactions for the user, patients should fully list the functional foods and drugs they are taking so that doctors and pharmacists can give accurate advice.
6. Some notes when using the drug Farizol
It is necessary to check whether the patient has a history of allergy to cefprozil, cephalosporins, penicillins or other drugs before cefprozil treatment is prescribed. The drug must be stopped immediately if the patient is allergic to the drug. Patients with antibiotic-associated diarrhea possibly a symptom of pseudomembranous colitis have been reported with most antibiotics, including cefprozil. Treatment with the antibiotic Cefprozil can alter the intestinal microflora and increase Clostridia. Caution should be exercised when administering cefprozil to patients taking diuretics because of its effect on renal function. For patients being treated or suspected of having impaired renal function, special monitoring and clinical and subclinical tests are required. Patients with a history of intestinal disease, especially colitis, need to be careful when using the drug. When cephalosporin antibiotics and cefprozil are used concurrently, a positive direct Coombs test may occur. Women who are pregnant use the drug only when absolutely necessary and must be monitored by a specialist. Small amounts of the drug have been found in breast milk. The drug should be used with caution in nursing women because of possible effects on the neonate. Patients should be warned about side effects when taking the drug if they drive or operate machinery, because dizziness may occur when taking the drug. The basic information about the drug Farizol in the above article is for reference only. This is a prescription drug, users should not use the drug on their own, but need to contact a specialist directly to get a suitable and safe prescription for the user.
