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Cimetidine mkp 300 belongs to the group of gastrointestinal drugs with the main ingredient being cimetidine. It is indicated for the treatment and prevention of advanced duodenal ulcer. However, during treatment with the drug may occur unwanted side effects such as diarrhea, headache, dizziness... Therefore, before using Cimetidine mkp 300, patients need to find out. carefully and follow the doctor's treatment..
1. Mechanism of action of the drug Cimetidine mkp 300
Cimetidine mkp 300 has the main ingredient cimetidine, with a formula similar to histamine. Cimetidine mkp 300 has the ability to resist H2 histamine competing with histamine at the H2 receptor in gastric parietal cells. From there, it helps to prevent the secretion of gastric juice by the causes of increased histamine secretion in the stomach. In addition, Cimetidine mkp 300 also reduces both the quantity and concentration of HCl in the gastric juice.
The inhibitory effect of H2 receptor of Cimetidine mkp 300 can reduce gastric acid secretion, which is stimulated to increase secretion by histamine, gastrin.
2. Indications and contraindications for using Cimetidine mkp 300
What diseases does Cimetidine mkp 300 treat? Cimetidine mkp 300 is indicated for the treatment of patients with active duodenal ulcer, or for the maintenance treatment of a benign progressive gastric ulcer or for the treatment of ulcerative gastroesophageal reflux disease. In addition, Cimetidine mkp 300 also helps in the treatment of pathological conditions of increased gastric secretion such as Zollinger-Ellison syndrome, multiple endocrine neoplasia, treatment of gastrointestinal bleeding due to peptic ulcer, and prevention of diarrhea. Gastrointestinal blood in people with severe diseaseHowever, Cimetidine mkp 300 may also be contraindicated in people who are hypersensitive to the ingredients of the drug.
3. Dosage and how to use Cimetidine mkp 300
The total dose of Cimetidine mkp 300 indicated for use is usually not more than 2.4g/day. The drug is taken with meals or at bedtime. The dose of Cimetidine mkp 300 used depends on the age and medical condition of the patient.
For adults treating peptic ulcer, the maintenance dose of 800mg/day should be applied at night before going to bed and done for 4 weeks if duodenal ulcer and 6 weeks if gastric ulcer. Treatment of gastroesophageal reflux: 400mg/day and used 4 times/day.
For children treated with Cimetidine mkp 300 with the recommended concentration from 10 to 15mg/kg/day. However, in this case, it must be prescribed by a doctor.
Note: The above recommended therapeutic dose for Cimetidine mkp 300 is for reference only. Therefore, before using Cimetidine mkp 300, patients need to be prescribed by a doctor.
If the patient using Cimetidine mkp 300 forgets a dose, use the missed dose as soon as you remember it. However, if the interval between the missed dose of Cimetidine mkp 300 and the next dose is too close, skip the missed dose. Patients should not double the dose of Cimetidine mkp 300, because it can cause drug overdose. To overcome the situation of missing doses of Cimetidine mkp 300, patients can set alarms or ask family members to remind them.
In case of accidental use of Cimetidine mkp 300 drug overdose compared to prescribed and appear some unwanted signs such as pupil dilation, dysarthria, rapid pulse, agitation, disorientation, respiratory failure breathing.... need to take the patient to see a doctor immediately. However, family members can apply some preliminary treatment measures such as gastric lavage, induce vomiting. Next, take the person to a medical facility to treat the symptoms.
4. Side effects when using Cimetidine mkp 300
Cimetidine mkp 300 may cause some unwanted side effects during treatment. However, with each case Cimetidine mkp 300 can occur in varying degrees from mild to severe.
Some common side effects caused by Cimetidine mkp 300 include: diarrhea, headache, dizziness, nausea, hallucinations, disorientation, gynecomastia in men, depression, restlessness, confusion. mixed... These side effects can occur at the beginning of treatment or after increasing the dose of the drug used. And often these reactions can be transient or subside over time.
However, in some cases Cimetidine mkp 300 can cause serious unwanted side effects with rare reactions. These reactions can appear within minutes of using Cimetidine mkp 300 or longer for a few days. When serious side effects appear such as: rash, temporary increase in liver enzymes, increase in serum creatinine, fever, allergic reaction to anaphylaxis, hypersensitivity vasculitis.... the patient should stop using Cimetidine mkp. 300 and requires immediate medical assistance.
Above is all the important information about Cimetidine mkp 300. If you have any further questions, the patient should directly discuss with the prescribing doctor for appropriate indications.
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