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Cefadroxil 500mg contains the main ingredient is Cefadroxil - an antibiotic belonging to the 1st generation cephalosporin group. Let's learn the uses of Cefadroxil 500mg and how to use this drug in the article below.
1. What is Cefadroxil 500mg?
Cefadroxil 500mg is a product of Domesco Medical Import Joint Stock Company with the main ingredient Cefadroxil 500mg - an antibiotic belonging to the 1st generation cephalosporin group.
2. Effects of Cefadroxil 500mg
Cefadroxil is indicated in the treatment of mild and moderate infections:
Urinary tract infections: gynecological infections, acute and chronic pyelonephritis, urethritis, cystitis. Respiratory tract infections: pharyngitis, tonsillitis, bronchopneumonia and lobar pneumonia, acute and chronic bronchitis, lung abscess, pleurisy, laryngitis, sinusitis, otitis media. Skin and soft tissue infections: Lymphadenitis, lying sores, abscesses, mastitis, erysipelas, cellulitis, furunculosis. Other infections: septic arthritis, osteomyelitis .
3. How to take Cefadroxil 500mg
Taking oral medications, patients need to take the drug with food to reduce side effects on the gastrointestinal tract.
Dosage:
Adults and children (> 40 kg): 500 mg - 1000 mg x 2 times/day depending on the degree of infection
Children over 6 years old (<40 kg): 500 mg, 2 times/day.
Elderly: need to check renal function and adjust dose in patients with renal impairment, initial dose is 500 mg - 1000 mg, subsequent dose is adjusted as follows:
Creatinine clearance 0 - 10ml/min, dose 500mg - 1000mg, the interval between 2 doses is 36 hours. Creatinine clearance 11 - 25 ml/min, dose 500 mg - 1000 mg, interval between 2 doses is 24 hours Creatinine clearance 26 - 50 ml/min, dose 500 mg - 1000 mg, interval between 2 doses is 12 hours.
4. Contraindications of Cefadroxil 500mg
Cefadroxil 500mg is contraindicated in the following cases:
Patients with a history of allergy to cephalosporin antibiotics and other components of the drug. Children under 6 years old.
5. Side effects of Cefadroxil 500mg
When using Cefadroxil 500mg, you may experience unwanted effects as follows:
Common side effects: gastrointestinal disturbances such as nausea, vomiting, abdominal pain, diarrhea.
Uncommon side effects:
Blood: Eosinophilia. Skin: Erythema, rash, urticaria, pruritus. Liver: Reversible increase in transaminases. Urology - genitourinary: Testicular pain, candidiasis, vaginitis, genital itching. Rare side effects:
Systemic: Fever, Anaphylactic reactions, serum sickness. Blood: hemolytic anemia, neutropenia, thrombocytopenia, positive Coombs test. Digestive: Pseudomembranous colitis, digestive disorders. Skin: Erythema multiforme, Stevens-Johnson syndrome, common pemphigus, toxic epidermal necrolysis (Lyell's syndrome), angioedema. Liver: Cholestatic jaundice, mild elevation of liver enzymes, hepatitis. Renal: Intoxication with temporary increase in blood urea and creatinine, reversible interstitial nephritis. Central nervous system: Convulsions (with high doses and with impaired renal function), headache, agitation. Athritis. Instructions on how to handle side effects:
When experiencing side effects, patients need to stop using Cefadroxil. In case of severe allergic or hypersensitivity reactions, supportive treatment should be instituted (maintenance of ventilation and use of adrenaline, oxygen, antihistamines, intravenous corticosteroids).
With mild pseudomembranous colitis side effects, it is usually only necessary to stop taking the drug. Moderate and severe cases of pseudomembranous colitis require fluid and electrolyte supplementation, protein supplementation and oral metronidazole, which is an antibacterial drug effective in treating C. difficile colitis.
6. Precautions when using Cefadroxil
Use caution when using the drug in patients with a history of allergy to penicillin group antibiotics due to the risk of cross-hypersensitivity reactions in people allergic to beta-lactam antibiotics. Use medication if an allergic reaction occurs. Before and during treatment with Cefadroxil, patients with renal impairment or suspected renal failure should be clinically monitored and appropriate laboratory tests performed. Long-term use of Cefadroxil may lead to the development of insensitivities. Therefore, it is necessary to monitor the patient carefully, stop using the drug if superinfection occurs. Care should be taken in the diagnosis of pseudomembranous colitis when broad-spectrum antibiotics are used in patients with antibiotic-associated severe diarrhea. Clostridium difficile-associated diarrhea has been reported with the use of antibiotics, ranging from mild to fatal diarrhea. Caution should be exercised when administering the drug to neonates and premature infants due to limited experience with Cefadroxil in this population. Ability to drive and use machines: The drug may cause headache, agitation (rare). Therefore, caution should be exercised when driving and operating machinery. Pregnancy: There have been no reports of adverse effects on the fetus, and the safe use of cephalosporins during pregnancy has not been established. Therefore, use the drug during pregnancy only when absolutely necessary. Lactation: Cefadroxil is excreted in breast milk in low concentrations with no effect on the nursing infant. However, care should be taken if the child has symptoms of diarrhea, thrush and a rash. Cefadroxil 500mg contains the main ingredient Cefadroxil - an antibiotic belonging to the first generation cephalosporin group. Cefadroxil is indicated in the treatment of mild and moderate infections. To ensure the effectiveness of treatment and avoid side effects, users need to strictly follow the instructions of the doctor, professional pharmacist.
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