Uses of Biocemet

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1. What is Biocemet?

Biocemet medicine has the main ingredients: Amoxicillin 500mg and Clavulanic Acid 62.5mg, made in the form of film-coated tablets, packed in a box of 1 aluminum bag, 2 blisters x 7 tablets.

2. What are the effects of Biocemet?

2.1. Indications Biocemet is indicated for use in the following cases:
Sinusitis, otitis media, tonsillitis. Cystitis, pyelonephritis, female genital infections, urethritis, septic abortion, intra-abdominal infection, pelvic infection or postpartum infection. Pneumonia, acute and chronic bronchitis, lung abscess. Cellulitis, boils, abscesses, wound infections. Postoperative infection Osteomyelitis. Dental abscess. 2.2. Contraindications Contraindications of Biocemet:
Biocemet is contraindicated for use in subjects with hypersensitivity to any component of the drug or cross-sensitivity to other antibiotics of the β-lactam family. Patients with a history of jaundice, penicillin-related liver failure, or infectious mononucleosis or lymphoma.

3. Dosage and how to use Biocemet

Dosage: Dosage of Biocemet depends on the age, weight or medical condition of the patient.
Biocemet is used in children up to 12 years old, dosed based on amoxicillin component and administered every 12 hours.
For disease status: Mild to moderate infections: use 25mg/kg body weight/day, severe infections: use 45mg/kg body weight/day. In children with renal impairment: 15 mg/kg body weight every 12 hours (if CICr is 10-30 ml/min) or once daily (if CICr level is less than 10 ml/min or on hemodialysis), during and at the end of the day Dialysis requires an additional dose of 15 mg/kg body weight.
For age or weight:
Children under 1 year: dose 30mg/kg body weight/day. Children under 1 year old and under 10kg: use 200/28.5, 2.5 mL/time; Children aged 1-6 years and 10-18kg: severe infections: 5-10 mL (200/28.5) or 2.5-5 mL (400/57); mild to moderate: 2.5-5 mL (200/28.5) or 2.5 mL (400/57). Children 6-12 years and 18-40kg: severe infection: 10-20 mL (200/28.5) or 5-10 mL (400/57), mild to moderate: 5-10 mL (concentration 200/28.5) or 2.5-5 mL (400/57). How to take Biocemet:
To minimize the possibility of gastrointestinal intolerance, Biocemet should be used at the beginning of a meal to optimize absorption. Drink plenty of water while using Biocemet to ensure proper hydration and urine output.

4. Biocemet drug interactions

Patients should avoid using Biocemet with the following drugs to avoid causing unwanted drug interactions:
Oral contraceptives: the use of Biocemet with Biocemet reduces the effectiveness of oral contraceptives. . There is also an increased rate of sudden bleeding or pregnancy. Allopurinol: Drug interactions occur that increase the rate of skin rashes, especially in patients with hyperuricemia. Probenecid: the active ingredient amoxicillin in Biocemet will reduce renal tubular secretion, leading to increased and prolonged serum concentrations of amoxicillin. Methotrexate: Biocemet reduces renal clearance of methotrexate and this increases methotrexate toxicity. Warfarin: increases INR.

5. Undesirable effects of the drug Biocemet

The use of Biocemet can cause many undesirable effects: anaphylaxis, fever, skin rash, pruritus, urticaria, serum sickness-like syndrome, angioedema, erythema multiforme, angioedema, acute generalized pustular rash, exfoliative dermatitis with bullous bullae, toxic epidermal necrolysis. Anorexia, gastrointestinal disturbances, abdominal discomfort, nausea, vomiting, flatulence, loose diarrhea, Clostridium difficile-associated colitis, glossitis, stomatitis, gastritis, pyelonephritis, Candida infections of mucous membranes and skin. Reversible leukopenia, reversible agranulocytosis, eosinophilia, prolonged bleeding time, thrombocytopenia, thrombocytopenic purpura, anemia, mild thrombocythemia, thrombocytopenia abnormal demand. Anxiety, confusion, insomnia, dizziness, headache, behavioral changes, agitation, hyperactivity, and convulsions were reversible especially in patients with renal impairment or high doses of Biocemet. Cholestatic jaundice, hepatitis, acute liver dysfunction, hyperbilirubinemia on tooth surface color: brown, yellow or gray.

6. Pay attention when using Biocemet

In the process of using Biocemet, patients need to pay attention to the following issues:
For children with liver failure: need to be careful about the dose when using Biocemet, and monitor liver function at the same time. . Periodic assessment of liver, kidney and hematopoietic status during prolonged treatment. Patients with a history of hypersensitivity to drugs such as: Cephalosporins, penicillin and some other drugs. For pregnant women, lactating women and children under 2 years old: Biocemet is not recommended. Undesirable effects when using Biocemet such as dizziness, allergic reactions, convulsions may affect subjects driving or operating machinery. Biocemet is manufactured and registered by Imexpharm Pharmaceutical Joint Stock Company, which belongs to the group of drugs for the treatment of parasites, anti-infectives, antivirals and antifungals. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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