Uses of Simbidan


What is Simbidan? Simbidan belongs to the group of cardiovascular drugs, with the main ingredient of the drug is Simvastatin 20mg. Simbidan is often indicated in cases of dyslipidemia or hypercholesterolemia. The drug information in the article below is not a substitute for a doctor's advice.

1. What effect does Simbidan have after use?

Simvastatin is a synthetic lipid-lowering agent that acts by inhibiting HMG-CoA reductase. HMG-CoA reductase, also known as 3-hydroxy-3-methylglutaryl-coenzyme Simbidan is an enzyme involved in the conversion of HMG-CoA into Mevalonate when the body synthesizes cholesterol. Simbidan has the ability to inhibit HMG-CoA reductase and inhibit cholesterol synthesis in the liver, thereby reducing protein and cholesterol in plasma. Therefore, the drug Simbidan is often indicated in cases of primary hypercholesterolemia, mixed hyperlipidemia, helping the body to increase HDL-C in patients with primary hypercholesterolemia with heterozygous familial or non-family nature, combined treatment with diet (helps increase body's total cholesterol, LDL-C, Apo B, Triglyceride),...
Drugs are usually indicated in cases dyslipidemia or hypercholesterolemia. In addition, Simbidan is also used to treat patients with coronary artery disease, and to prevent ischemic heart disease when cholesterol in the blood increases. Care should be taken when prescribing Simbidan to pregnant or lactating women.

2. Instructions for using Simbidan and drug dosage


Simbidan medicine is prepared in capsule form so you should use it orally. Before using the drug, you should carefully read the accompanying instructions for use and follow the instructions of your doctor. For patients just starting treatment at the initial stage, Simbidan should be used at the lowest effective dose, then if necessary, continue to adjust the drug according to the body's response. When increasing the pharmacy, it is necessary to increase in batches at intervals of not less than 4 weeks. Besides, it is necessary to continuously monitor the patient to detect early adverse reactions that the drug may cause.
Patients treated with Simbidan and Amiodarone should not take more than 20mg/day. In order to achieve the best treatment effect, patients should be instructed on how to combine Simbidan with a standard cholesterol-lowering diet during the duration of the drug. Simbidan can be used at any time of the day.
The dose of Simbidan drug will depend on LDL-C concentration, treatment goals, and the body's response to the drug. Therefore, the dose of the drug is different for each person. Dosage at the beginning of use is 10mg, taken once a day. Then, based on the body's response to the drug and the needs of the patient, increase the dose slowly in batches. The maintenance dose of Simbidan is from 10-80mg/day. During the use of the drug, it is necessary to monitor blood lipid levels regularly within 4 weeks, based on the test results, the doctor may consider adjusting the dose.
The drug should not be prescribed for young children because there are no documents proving the level of safety for this group of people.

3. Overdose or missed dose of Simbidan


In case you miss a dose of Simbidan, take it as soon as you remember. The medication fluctuates within 1 to 2 hours of the time your doctor ordered it. So if the time of taking the supplement is too close to the time of taking the next dose, why should you discard the lost material and continue taking the medicine as usual. You should never double the dose to make up for the lost dose.
To date, there is no specific treatment for cases of Simbidan overdose. The most commonly used treatment is symptomatic relief and necessary supportive measures. However, hemodialysis cannot be used to increase clearance because the drug is strongly bound to plasma proteins.

4. Unwanted side effects of Simbidan


The side effects of Simbidan will vary depending on the patient's condition and the extent of the disease.
Digestive system: Abdominal pain, loss of appetite, digestive disorders, constipation, diarrhea, heartburn, nausea, ,pancreatitis, jaundice, hepatitis, liver failure, cirrhosis, and liver cancer, changes in the amount of fat in the liver,... For muscles and bones: Muscle atrophy, myositis, cramps, bone pain, muscle weakness, muscle damage, joint pain,... For the nervous system: Insomnia, memory loss, tinnitus, headache, dizziness, anxiety, hallucinations, depression, imbalance, memory impairment, confusion, mental disorders,... Endocrine system: Increased HbA1c levels In the blood, increased blood glucose,.. Allergic reactions: Burning, itching, pimples, swelling (face, lips, tongue), difficulty breathing, shortness of breath, wheezing, possible shock, .. Eyes: Vision loss, progressive clouding, blurred vision, eye muscle weakness, .. Other: Loss of libido, impotence, breast tenderness,... If the patient appears one of the above symptoms need to bring the patient to the medical center immediately to receive help from specialists. Simbidan is effective in cases of dyslipidemia or hypercholesterolemia. However, besides the benefits that the drug brings, there are still unwanted side effects that can occur. Therefore, before using the drug, the patient should carefully study the information about the drug as well as consult with the doctor and medical professional.

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