Uses of Negacef 125

Negacef 125 is an antibiotic with the main ingredient Cefuroxime, used in the treatment of mild to moderate infections of the respiratory tract, urogenital tract or skin... and use according to the instructions of the doctor will bring the best treatment effect.

Negacef 125 is prepared in the form of a powder pack mixed with water with the main ingredients:
Cefuroxim (Cefuroxime axetil) 125 mg. Excipients: Sucrose, Mannitol, Polyacrylic polymer, Sucralose, Potassium hydroxide, Propylparaben, Methyl paraben, Colloidal silicon dioxide, ethyl vanillin, acetone and strawberry flavor just enough for 1 pack. Cefuroxime is a second-generation cephalosporin antibiotic with the mechanism of binding to necessary target proteins, thereby inhibiting bacterial cell wall synthesis. The effective antibacterial spectrum of Cefuroxime is quite wide, including: Beta-lactamase/Cephalosporinase-producing bacteria, Gram-positive cocci, aerobic and anaerobic Gram-negative cocci, penicillinase-producing Staphylococcus, Gram-negative intestinal bacteria..
Currently, Cefuroxim has been resistant to bacteria such as most Enterococcus strains, Staphylococcus strains including Staphylococcus aureus, methicillin-resistant Staphylococcus epidermidis, Listeria monocytogenes.

Negacef 125 main use is to treat mild to moderate infections for the following cases:
Upper respiratory tract infections: pharyngitis, sinusitis, otitis media, tonsillitis. Lower respiratory tract infections: Acute or chronic bronchitis, pneumonia. Skin and tissue infections: Skin pustules, boils, impetigo. Urinary tract infections: Nephritis, pyelonephritis, cystitis, uncomplicated acute urethritis due to gonococcal infection. Genital inflammation: Cervicitis, genital inflammation in gonorrhea.

People with hypersensitivity to the ingredients of the drug. History of allergy to cephalosporin antibiotics. People with severe renal impairment.

For adults:
Dose for bronchitis, pneumonia: Take 4 packs (500mg)/time x 2 times/day. Dose for urinary tract infections: Take 1 sachet (125mg)/time x 2 times/day. Dose for infections at other sites: Take 2 sachets (250mg)/time x 2 times/day Dose for uncomplicated gonorrhea: A single dose of 1g/time is recommended. For children:
Usual dose: Take 1 sachet (125mg)/time x 2 times/day or 10mg/kg/time x2 times a day. Take up to 2 sachets (250mg)/day. Children > 2 years old with otitis media: Take 2 sachets (250mg)/time x 2 times/day or 15 mg/kg/time x 2 times/day. Take up to 4 sachets (500mg)/day. To avoid side effects of the drug, especially when used in children, it is necessary to carefully read the treatment instructions on the drug packaging or consult the treating doctor. Do not arbitrarily change the way of use and dosage without the consent of your doctor or pharmacist.

Side effects
Excessive or prolonged use of the drug, especially in young children, can cause effects such as:
Common: Skin rash, itching, diarrhea. Uncommon: Mild fever, urticaria, pruritus, nausea, vomiting, mild anaphylactic reactions. When experiencing unwanted effects, the drug should be stopped immediately and notified to the treating doctor or immediately to the nearest medical facility for timely treatment.
Notes on drug use in subjects
Be careful when using Negacef 125 in the following cases: People with a history of allergy to Cephalosporin antibiotics, penicillin allergy or some other drug groups. Patients with impaired liver and kidney function should be checked before and during drug use. Use with caution in people with digestive diseases, especially colitis.
Pregnant or lactating women: Currently, there is no clear evidence to evaluate the potential for complications in pregnancy, it is necessary to weigh the benefits and harms when using the drug. Cefuroxime may be excreted in human milk, but at low concentrations, caution should be exercised when treating nursing mothers.
Drivers or workers who operate machinery should avoid using drugs during and before work because it can cause dizziness.

Interactions with other drugs
Stomach antacids, H2 antihistamines should be taken at least 2 hours apart with Negacef 125 because it can increase the pH in the stomach. Sodium bicarbonate, Ranitidine are drugs that can reduce the bioavailability of the drug. Concomitant use of Negacef 125 with Aminoglycoside antibiotics can cause nephrotoxicity.

The medicine is stored in a cool and dry place, the room temperature is below 30 degrees Celsius, avoid direct exposure to high temperature or sunlight. To medicines out of reach of children.
Above is information on usage, dosage, indications for treatment, side effects and notes when using Negacef 125. Carefully read the instructions for use and strictly follow the instructions of the treating doctor. to achieve the best treatment results.