Uses of Ficdal

Ficdal's main ingredient is Doxycycline hyclate, this is a broad-spectrum antibiotic with bacteriostatic effect, a broad spectrum of action against Gram-negative and Gram-positive bacteria, some bacteria resistant to beta-lactam drugs such as Coxiella burnetii , Chlamydia spp,...
Ficdal acts through the mechanism of inhibiting bacterial protein synthesis, changing properties in the plasma membrane.
Ficdal drug is well absorbed from the gastrointestinal tract after oral administration, distributed mostly in tissues and secretions, urine and prostate gland. Metabolized in the liver, then eliminated in feces and urine.

Ficdal is indicated for the treatment of the following infections:
Pneumonia caused by Streptococcus bacteria, Pneumococcus, Staphylococcus, Haemophilus influenzae,... Sinusitis, pharyngitis, tonsillitis caused by Streptococcus, Staphylococcus, Haemophilus influenzae , Pneumococcus. Genitourinary tract infections. Skin and soft tissue infections caused by strains of Staphylococcus aureus and albus; E.coli; Streptococcus; Klebsiella aerobacter group. Gastrointestinal infections caused by bacteria E.coli, Shigella, Salmonella.

Ficdal drug should not be used in the following cases:
Allergy to Doxycycline, Tetracycline or any other ingredient of the drug. Pregnant and lactating women should not use Ficdal. Children under 8 years of age are not indicated for the use of Ficdal. Note when using Ficdal
Ficdal can cause liver toxicity, so it is necessary to monitor liver function before and during use. Avoid concomitant use of Ficdal with hepatotoxic drugs. Patients need to use the right dose and not abuse the drug to avoid fungal superinfection, drug resistance in sensitive bacteria. Pregnant and lactating women must be prescribed and strictly monitored by a doctor when taking the drug. Patients with high blood pressure when taking Ficdal may have a photodynamic response to sunlight. Children taking Ficdal may experience increased intracranial pressure along with fontanelles.

Interactions of Ficdal drugs that may occur during use are as follows:
Concomitant use of Ficdal with antacids containing aluminum, calcium, or magnesium may reduce the effectiveness of the drug. Co-administration of Ficdal with Iron and Bismuth subsalicylate, may reduce the bioavailability of the drug. Co-administration of Ficdal with barbiturates, phenytoin and carbamazepine may reduce the half-life of the drug and increase toxicity on the liver and kidneys. Co-administration of Ficdal with Warfarin enhances the effect of anticoagulants.

How to use
Patients need to take Ficdal during or after meals with plenty of water in an upright or standing position to avoid gastrointestinal irritation. Avoid taking with milk, because it can reduce the effect of the drug. Dosage in adults
Attacking dose: 2 tablets (100mg tablets) on the first day of treatment. The maintenance dose is then 1 tablet (100mg)/day. Drink at the same time. Severe infections: take 2 tablets (100mg tablets)/time/day. Treatment of infections caused by Streptococcus (streptococcal): 10 consecutive days to prevent rheumatism or glomerulonephritis. Gonococcal infection: The first day 2 tablets (100mg) in the morning, 1 tablet (100mg) at night before going to bed; The next day 1 tablet (100mg) x 2 times / day for 3 days. Genitourinary and urinary tract infections: 1 tablet (100mg) x 2 times/day. Use for at least 10 days. Patients with renal impairment do not require dose adjustment of Ficdal. Dosage in children
Children over 8 years old: dose 4mg/kg/day. Use continuously for 7-10 days. Note: The above dosage is for reference only, patients should strictly adhere to the dosage prescribed and recommended by the doctor.

When using Ficdal medicine may experience some unwanted side effects as follows:
Nausea, vomiting, diarrhea. Glossitis, inflammation of the oral mucosa. Inflammation of the rectum. Esophageal ulcers when taking capsule form. Increase liver enzymes. Decreased neutrophils, increased eosinophils. In summary, Ficdal is a broad-spectrum antibiotic that is active against many strains of aerobic, anaerobic, Gram-negative and Gram-positive bacteria. The drug is specific to many sensitive bacteria, so patients should take the drug according to the indications to avoid fungal infections and drug resistance.
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