Should you use diapers 24/7? Using diapers every day for your baby is not recommended. Babies' skin is very sensitive and needs to be treated gently. Using diapers all day can cause rashes and skin irritation. Therefore, you should not wear diapers all day. If you have to use it frequently for some reason such as traveling, then choose diapers carefully. Nowadays, many companies are making diapers that are skin-friendly and soft on the skin. Some even have air holes to keep your baby's skin dry and comfortable.