Vertucid topical is a combination of two drugs Adapalene and Clindamycin, which works to treat boils and acne. In particular, Adapalene is a form of vitamin A that works to prevent the accumulation of sebum, clog pores and allow natural exfoliation of the outer skin layers. The rest, Clindamycin is an antibiotic that penetrates the skin to kill acne-causing bacteria.