Tenofovir alafenamide (abbreviated TAF, common brand names Hepbest, Teravir) is an antiviral drug of the nucleotide reverse transcriptase inhibitor (NtRTI) group used to treat chronic hepatitis B virus infection in adults and children over 12 years old. TAF prevents the hepatitis virus from multiplying in the body, thereby helping to reduce liver damage and control the disease.

Good news for patients with chronic HBV is that at the end of 2016, the US Food and Drug Administration (FDA) recognized the new generation Tenofovir (Tenofovir alafenamide, TAF) as highly effective and safe on the kidneys and bones compared to the old generation TDF.