Sotalol is used to treat irregular heartbeats. Sotalol belongs to the class of antiarrhythmic drugs. It works by acting on the heart muscle to improve heart rate. Sotalol comes in pill form. Sotalol (Betapace) is usually taken twice a day and sotalol (Betapace AF) is usually taken once or twice a day. The following article will provide information about the uses, indications and notes when using Sotalol.