As you age, collagen levels decrease and wrinkles begin to appear. The resulting wrinkles tend to be most noticeable around the thin skin areas of your face, such as your forehead, eyes, and mouth. Collagen loss occurs naturally over time, but certain lifestyle habits can speed up the aging process. In this article, we will explore the causes of mouth wrinkles and answer the question: What should you do to get rid of mouth wrinkles?