In recent years, the quantitative NT-proBNP test has been widely used in the diagnosis, treatment monitoring, prognosis and screening of heart failure and many other cardiovascular diseases.

Heart failure is a pathological condition in which cardiac output is insufficient to meet the body's oxygen needs in all patient situations. Heart failure is the final common path of most cardiovascular diseases. Patients with heart failure will have reduced functional capacity, reduced quality of life, and will need different levels of support depending on the level. In addition, patients with severe heart failure will face a high risk of death due to arrhythmias and episodes of decompensated heart failure. Early and accurate diagnosis of heart failure is still difficult if based only on clinical signs, because they are often nonspecific. Therefore, NT-proBNP test is used for screening, early diagnosis and monitoring of heart failure treatment.