Total hysterectomy is a major surgery, it will greatly affect women's endocrine. Therefore, before deciding to completely remove the uterus, the doctor will consider and prioritize the benefits in which cases should be completely removed.

Molar pregnancy is a pathological condition of the placenta, in which part or all of the placenta degenerates into large and small fluid-filled sacs, which adhere to each other in clusters like frog eggs. Hysterectomy in patients with molar pregnancy may be indicated to reduce the risk of complications of trophoblastic cancer.