Yellow nail syndrome is a rare condition that affects your fingernails and toenails. People with this type of nail condition may also have problems with their lungs and lymphatic system, as the buildup of lymph under the nails causes them to turn yellow. It can occur at any age but is most common in people over 50.

The effects of cancer treatment involve not only the diseased organ but also many different parts of the body. Dark skin during chemotherapy and painful nails with cancer are among the changes that can be experienced in patients.