Abnormal uterine bleeding is an abnormality of the menstrual cycle that occurs in women of reproductive age. Diagnosis of abnormal uterine bleeding is important in assessing the bleeding pattern and severity, thereby providing specific treatment.

Precocious puberty is when the first signs of puberty are detected in girls before the age of 8 and in boys before the age of 9-10. The consequence is a decrease in height in adulthood, in addition to causing psychological disorders for children because of unusual changes in the body compared to their peers. There are many ways to diagnose precocious puberty in children, one of which is measuring the concentration of Gonadotropin in the blood serum.