Pancreatic neuroendocrine tumors can cause a variety of symptoms, depending on the type of hormone they produce. If the tumor is malignant and spreads to other parts of the body, the cancer can become very serious.

Diagnosis of endocrine pancreatic tumors is based on blood sugar quantification during hypoglycemia, increased endogenous insulin, and imaging methods will help determine the location of endocrine pancreatic tumors, which is useful for surgery.