Cyclical vomiting syndrome (CVS) in adults is a disorder characterized by sudden recurrent episodes of nausea, vomiting, and abdominal pain, separated by different periods of normal health.

Alternating patterns of disease and disease-free periods help distinguish cyclic vomiting syndrome (CVS) from other nausea and vomiting disorders. This pathology is increasingly recognized in adults and leads to significant morbidity and poor quality of life.