Hi doctor. Currently, I have chest and back pain, difficulty breathing, chest tightness, pain or salivation in the epigastrium. Throat is itchy and coughs with mucus. May I ask if I have acid reflux and do I need an endoscopy? Thanks for the advice doctor.

In 1853, Rudolf Virchow first used the term “amyloid” to describe deposits in the brain that closely resembled starch after they were stained with iodine and sulfuric acid. Amyloidosis comprises a heterogeneous group of disorders characterized by extracellular deposition of fibrillar fibers that aggregate into a three-dimensional ß-lamina (anti-patterned sheet) in tissues, disrupting normal tissue structure and function.