Duavee is a prescription medication that contains a mixture of estrogen and bazedoxifene. Duavee is effective in improving moderate to severe hot flashes during menopause in women entering middle age. Since the ovaries normally stop producing estrogen in women between the ages of 45 and 55, the drop in estrogen levels in the body causes unpleasant symptoms during menopause. Accordingly, actively supplementing with estrogen can help women feel more comfortable during this period.