Opioid pain relievers are widely used to relieve moderate to severe pain for a variety of reasons when other pain relievers are less effective, contributing significantly to improving the patient's quality of life.

The colon is the large intestine (colon) and the rectum is the last part of the intestine where stool is stored. Ulcerative colitis is a chronic inflammation of the colon and rectum. Small sores can develop on the lining of the colon, bleed, and form pus. In this article, we will learn more about the treatment-resistant or drug-dependent cases of ulcerative colitis.