Hypothermia therapy for the treatment of hypoxic-ischemic encephalopathy has been shown to be effective in protecting the brain, reducing mortality and neurological sequelae in asphyxiated infants.

If not diagnosed and treated promptly, neonatal asphyxia can be life-threatening or leave serious sequelae. Therefore, neonatal resuscitation plays an extremely important role.

According to the World Health Organization (WHO), birth asphyxia or birth asphyxia occurs in 2 to 10 out of every 1,000 babies born at term, and more in premature births. WHO estimates that 4 million neonatal deaths occur each year due to birth asphyxia, accounting for 38% of deaths in children under 5 years of age.