A drug interaction is a change in the effect of a drug under the influence of one or more other drugs, herbs, foods, beverages, or other chemicals. This changes the effectiveness of the drug and can even create serious drug interactions.

Alpha blockers are not the preferred drug class in the treatment of hypertension. The drug is often used in combination with the preferred drug classes when the patient's blood pressure is not controlled.

Blockadip is a drug used in the treatment of high blood pressure. Blocadip can be used alone or in combination with other antihypertensive drugs such as diuretics, beta-blockers to bring about the best treatment effect.