Hypertension (high blood pressure) causes kidney failure and conversely, kidney failure causes high blood pressure. The problem is to control blood pressure to avoid kidney failure. At the same time, it is necessary to treat kidney failure well to limit hypertension.

There are many risk factors for hypertension in CKD patients, such as: decreased sodium excretion, increased sympathetic activity, increased renin-angiotensin system (RAS) activity. ), increased synthesis of endothelin, imbalance of prostaglandins or kinins, increased synthesis and decreased nitric oxide.