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Lopran is an anti-diarrheal medicine with the main ingredient Loperamide hydrochloride. So Lopran is taken before or after meals? Let's learn about how to use the drug in the article below.1. What is Lopran?
Lopran is a medicine for the treatment of acute diarrhea with the main ingredient Loperamide hydrochloride. Loperamide is used for the symptomatic treatment of acute diarrhea of unknown etiology and certain chronic diarrheal conditions.Loperamide binds to opioid receptors in the intestinal wall, reducing mucosal irritation and stimulation of gastrointestinal spasm. This is a synthetic form of opioid that, in normal doses, has little effect on the central nervous system.
2. Indications of the drug Lopran
Lopran is indicated in the following cases:
Second-line indication for the treatment of acute uncomplicated diarrhea in adults or to reduce waste volume following an ileostomy or colectomy. Lopran should not be used in the routine treatment of acute diarrhea in children and is not a substitute for oral rehydration and electrolyte therapy.
3. Contraindications of Lopran
Lopran is contraindicated in the following cases:
Hypersensitivity to loperamide. When necessary avoid inhibition of intestinal motility. Liver damage. Severe colitis, pseudomembranous colitis. Dysentery syndrome. Distention .
4. How to take Lopran
Lopran drug taken before or after eating? Lopran is used orally, immediately after diarrhea, regardless of before or after eating.
Dosage:
Adults
Acute diarrhea: Initially take 4mg, then take 2mg with each loose stool, use the drug for a maximum of 5 days. The usual dose is 6-8mg/day. Maximum dose 16mg/day. Chronic diarrhea: 4mg dose, then 2mg each time loose stool until diarrhea stops. Maintenance dose is 4 to 8 mg/day. Maximum dose 16mg/day. Children: Lopran is not routinely used in children for the treatment of acute diarrhea.
Children < 6 years: Not recommended. Children 6 to 8 years old: 2mg x 2 times/day. Children 8 to 12 years old: 2mg x 3 times/day. Maintenance dose: 1mg/10kg body weight, only taken after 1 bowel movement.
5. Undesirable effects of the drug Lopran
Some side effects when using Lopran such as:
Common: Constipation, abdominal pain, nausea, vomiting.
Uncommon:
Body as a whole: Dizziness, fatigue, headache Digestion: Abdominal bloating, dry mouth. Rare:
Gastrointestinal: Paralytic bowel obstruction. Skin: Allergic.
6. Precautions while using Lopran
Use with caution in patients with impaired liver function or ulcerative colitis. Within 48 hours, stop taking the drug if no results are seen. Monitor stool volume, bowel movements, and body temperature. Monitor abdominal distension. Ability to drive and use machines: Caution should be exercised due to the side effects of fatigue, dizziness and headache. Pregnant women: The drug should not be used by pregnant women. Lactation: Since loperamide is excreted in very little milk, it can be used in nursing mothers but in low doses. Above is important information about Lopran. Before using, you need to read the instructions carefully or consult your doctor for appropriate indications.
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