What is Haginat 500 used for?

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Haginat 500 is a commonly used antibiotic. The drug is effective in the treatment of diseases related to the respiratory tract and diseases of the Ear, Nose and Throat.

1. What is Haginat 500?

Haginat 500 belongs to the group of drugs that treat parasites and fight infections. Haginat 500 contains the active ingredient Cefuroxime Axetil. This medication is used to treat upper and lower respiratory tract infections.
The main ingredient of the drug is pharmacodynamics Cefuroxime. In addition, there are other excipients such as: ß-cyclodextrin, white sugar, mannitol, aspartame, aerosil, anhydrous citric acid, modified starch, sodium citrate, sodium benzoate.

2. Effects of Haginat 500

Cefuroxime is a semi-synthetic broad-spectrum antibiotic belonging to the cephalosporin group of drugs. Haginat injection is the sodium salt form, the oral drug is the acetil ester form.
Cefuroxime axetil is a prodrug of the pharmacokinetics of Cefuroxime. This active substance has little antibacterial activity when not hydrolyzed to cefuroxime. Only after the drug enters the body is absorbed. Cefuroxime is a component with good antibacterial activity, the reason being that it inhibits bacterial cell wall synthesis by binding to essential target protein receptors. Cefuroxime has very good antibacterial activity that is characteristic against many common pathogens, including beta-lactamase/cephalosporinase-producing strains of both Gram-negative and Gram-positive bacteria. Cefuroxime is particularly stable to many enzymes such as beta-lactamase enzymes of Gram-negative bacteria.
Effects of haginat 500 in the treatment of the following cases:
Treatment of infections caused by susceptible bacteria in the following cases: Upper and lower respiratory tract infections including: sinusitis, oral infections, inflammation pharyngitis, nasopharyngitis, tonsillitis, otitis media, pneumonia, acute bronchitis and exacerbations of chronic bronchitis. Genitourinary tract infections: nephritis, pyelonephritis, urethritis, cystitis or gonorrhea. Skin and soft tissue infections: pustules, boils, impetigo.

3. Dosage of Haginat 500

Medicine Haginat 500 used for 5-10 days, taken after eating.
3.1 For adults Most infections 250mg twice daily. Typhoid fever 500 mg x 2 times/day; Genitourinary infections 125mg x 2 times/day; Mild to moderate lower respiratory tract infections: 250mg/time x 2 times/day; severe degree, suspected pneumonia is 500mg/time x 2 times/day; Treatment of pyelonephritis with a dose of 250mg/time x 2 times/day; Treatment of uncomplicated gonorrhea with a single dose of 1g/time/day. Early stage Lyme disease with a dose of 500mg x 2 times/day, maintenance treatment for 20 days. 3.2 For children Most infections use dose 125mg/time x 2 times/day, maximum 250mg/time Treatment of typhoid fever dose is 250mg/time x 2 times/day Children from 2 years of age and older have inflammation Middle ear or severe infections dose is 250mg / time x 2 times / day. Note: Haginat 500 c can only be used under the prescription of a doctor.

4. What should I do if I overdose on haginat 500?

Do not exceed the prescribed dose. Taking Haginat 500 more than the recommended dose will not improve symptoms and may cause toxicity or serious unwanted effects.
If you suspect that you or someone else may have overdosed on Haginat 500 go to the emergency room at the nearest hospital or care facility. When you go to the doctor, you should bring the box, cover, or label of the medicine with you to help the doctor with the necessary information.
Acute overdose: Most drugs Haginat 500 only cause effects on the digestive system such as nausea, vomiting and diarrhea. However, the reaction may increase neuromuscular excitability and convulsions, especially in patients with renal impairment.
Overdose management: Protect airway, assist ventilation and establish intravenous line. If seizures develop, treatment should be discontinued immediately and anticonvulsant therapy instituted if clinically indicated. Also, hemodialysis or dialysis techniques can remove drugs from the blood, but most of the treatment is supportive or symptomatic.
Do not arbitrarily give your Haginat 500 to others even though you know they have the same medical conditions or it looks like they may have a similar condition. This can lead to an overdose or poisoning of Haginat 500.

5. Note when using Haginat 500

Contraindicated in people with hypersensitivity to Cephalosporin antibiotics.
Precautions for use
Special care should be taken when using it for people who have a history of allergic reactions to penicillins. Consider pseudomembranous colitis in patients with severe diarrhea during or after antibiotic therapy. Caution should be exercised in people being treated concomitantly with potent diuretics, who have a history of colitis. During pregnancy, Haginat 500 crosses the placenta with caution when used in this population. If necessary, consult your doctor to weigh the benefits and risks.
Lactation period Haginat 500 is likely to be excreted in breast milk, so it should be used with caution in this subject. If necessary, consult your doctor, pharmacist to weigh the benefits for the mother and the risks for the baby.
Other special populations (elderly, children, allergies) Cephalosporin drugs can interact with drugs to change the drug's ability to work or increase the effect of unwanted effects. It is best to write a list of all the medicines you are taking (including prescription, nonprescription and dietary supplements) and show them to your doctor or pharmacist.
Do not arbitrarily use Haginat 500, stop or change the dose of the drug without the permission of the doctor.
Concomitant treatment of Cefuroxime with Aminoglycosides or strong diuretics will cause nephrotoxicity, Probenecid slows renal elimination of Cefuroxime, makes Cefuroxime plasma concentrations higher and stays longer.

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