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Butorphanol is a drug that acts on the human brain to help reduce pain. However, this is not a commonly used pain reliever. So what is the mechanism of action of Butorphanol and what is the use of Butorphanol?
1. What is Butorphanol?
Butorphanol is a narcotic pain reliever similar to morphine.
2. Butorphanol's mechanism of action
Mechanism of action Butorphanol is a direct action on certain areas of the brain, helping the body reduce pain.
This narcotic pain reliever reduces the effects of other narcotic analgesics, causing withdrawal syndrome in cases of narcotic dependence. Therefore, patients who are using narcotic pain relievers in high doses or on long-term use should not use it with Butorphanol.
Butorphanol là loại thuốc giảm đau tác dụng trực tiếp lên vùng não bộ
3. Uses of Butorphanol
Butorphanol is indicated for the treatment of moderate to severe pain, including postoperative pain, myalgia, headache and migraine.
4. Dosage forms of the drug Butorphanol
Butorphanol has the following dosage forms:
Butorphanol nasal spray form (intramuscular or intravenous injection)
5. Instructions for using Butorphanol
For Butorphanol spray, the patient needs to clean the nose very gently before spraying. Make nasal spray according to the instructions of the doctor/pharmacist, need to understand the nozzle installation procedure before use, if the nozzle has not been used for 48 hours, it is necessary to reinstall the nozzle again before spraying. medicine.
Each time spray one nostril or spray as prescribed by the doctor, after 60-90 minutes but the pain does not decrease, the doctor will instruct the patient to spray a second time with the other nostril. In some cases, patients need to make 2 sprays / 1 nostril at the same time, then the patient needs to lie down immediately because there may be dizziness, lightheadedness when taking high doses.
Butorphanol injection can be self-injected at home according to the instructions, but absolutely do not inject butorphanol yourself when the patient and family members do not know how to inject, how to remove needles and how to dispose of used instruments. used
Butorphanol dạng tiêm có thể tự tiêm tại nhà nhưng theo đúng hướng dẫn của bác sĩ
6. Dosage of Butorphanol
6.1 Dosage of Butorphanol for adults Butorphanol used in anesthesia:
Before surgery: start with a dose of 2mg IM 60-90 minutes before surgery. Balanced Anesthesia: Start with 2 mg IV immediately before anesthesia and/or increase from 0.5 to 1 mg during anesthesia. Butorphanol for labor: starting with 1-2mg IV or IM once, repeated every 4 hours to increase analgesic effect (if needed).
Butorphanol for general pain relief: start with 1mg intravenously once, depending on the severity of the pain, adjust the dose in the range of 0.5-2 mg.
Butorphanol truyền vào cơ thể bằng tiêm bắp hoặc tiêm tĩnh mạch
6.2 Butorphanol dosage for children Currently, there are no specific studies on the use of Butorphanol and the dosage of the drug for children. Therefore, doctors will often weigh the effects of Butorphanol with the possible risks when used for children.
7. Butorphanol side effects
Butorphanol can cause a drop in blood pressure, especially in the first hour after use, causing dizziness, lightheadedness, possibly fainting. Therefore, the patient should sit or lie down immediately after using the drug regardless of the route of administration.
Butorphanol can cause withdrawal syndrome when used regularly for a long time or in high doses. Symptoms of drug discontinuation syndrome include: restlessness, runny nose, watery eyes, trouble sleeping, abdominal pain, muscle pain, nausea, vomiting, rapid breathing, tachycardia ... appear when the patient suddenly stop using the drug. To prevent this, your doctor will prescribe a gradual decrease in the dose of the drug before stopping it completely. Therefore, when using the drug, the patient absolutely must not stop taking the drug, increase or decrease the dose without consulting the doctor.
Although rare, patients can develop drug addiction.
When taking the drug for a long time, the drug may no longer work as it used to (the pain continues or becomes worse), then it is necessary to notify the doctor immediately to adjust the dose.
Khi ngưng thuốc sau thời gian dài sử dụng có thể gây ra các tác dụng phụ
8. Notes when using Butorphanol
Do not drink alcohol, smoke or use stimulants while taking the drug. Follow your doctor's treatment instructions. Do not increase/decrease the dose arbitrarily. Pay special attention when using the drug if the patient is or has ever used drugs. Butorphanol nasal spray can cause drowsiness, dizziness, fainting, especially often in the first time after using the drug. In case of accidental overdose, call an ambulance immediately or take the patient to the nearest medical facility for assistance. If it is too close to the time for the next dose, skip it and use the next dose as usual. Do not double the dose on your own. Butorphanol medicine is stored at room temperature, away from direct light, do not leave the medicine in the bathroom or in the freezer compartment, out of the reach of children. For detailed advice, please come directly to Vinmec health system or register online HERE.
