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What does Bezlotoxumab do, is it a treatment for Clostridium difficile infection? In fact, the drug Bezlotoxumab is a monoclonal antibody, indicated for use in combination with antibiotics to treat Clostridium difficile infections when the patient has a high chance of re-infection.
1. What are the effects of Bezlotoxumab?
Bezlotoxumab drug has the main ingredient Bezlotoxumab, which is a monoclonal antibody that prevents bacteria from infecting host cells.Bezlotoxumab is available as a 25mg/ml injection and is packaged in 1000mg/40ml vials. It is indicated for use in adults (over 18 years of age) to prevent recurrent Clostridium difficile infections, in case of Patients who are being treated for Clostridium infections with antibiotics and are at high risk of recurrent infections.
2. Usage and dosage of the drug Bezlotoxumab
Bezlotoxumab is given by injection and is administered by a healthcare professional or doctor. Dosage is 10mg/kg body weight intravenous infusion over 1 hour. The drug should only be administered as a single dose because repeat dosing studies have not been conducted. People with liver failure, kidney failure do not need to adjust the dose.
Note, Bezlotoxumab is not an antibacterial and is not indicated for the treatment of Clostridium difficile infections. The drug is used in combination with antibacterial drugs to treat Clostridium difficile infections.
3. Side effects and some notes when using Bezlotoxumab
Bezlotoxumab can cause some unwanted side effects such as nausea, fever, headache, heart failure and infusion-related reactions. Therefore, if there is any abnormality after infusion, the patient and the patient's family should immediately contact the medical staff or the doctor.
Do not use Bezlotoxumab in people with hypersensitivity to the ingredients of the drug and children under 18 years of age because studies on the efficacy or safety of the drug in children have not been available. People with congestive heart failure should only use Bezlotoxumab when necessary, because the drug can cause heart failure. Pregnant and lactating women should not use Bezlotoxumab because of limited data in this population, and should only be used in nursing mothers after weighing the benefits and risks to the patient. with mothers and infants. To date, there have been no reported interactions between Bezlotoxumab and other drugs of mild to moderate severity and severity. Bezlotoxumab is used to prevent recurrent Clostridium difficile infections in patients who are being treated with antibiotics for Clostridium difficile infections but have a high likelihood of recurrence of the infection.
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