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Alunbrig is a prescription medicine used to treat certain types of non-small cell lung cancer that have spread to other parts of the body, in people who have been treated with Crizotinib and their condition disease has not improved. So what is Alunbrig?
1. What is Alunbrig? The effect of the drug Alunbrig
Alunbrig, also known as Brigatinib, is a cancer drug that interferes with the growth and spread of cancer cells in the body. Alunbrig is used to treat non-small cell lung cancer that has spread to other parts of the body (metastatic) when treatment with other cancer medicines has not responded.Alunbrig is used only if the lung cancer condition has a specific genetic marker (an abnormal "ALK" gene). Your treating doctor will order laboratory tests to check for this gene for you.
2. Warning when using Alunbrig
Alunbrig can cause serious side effects such as lung problems, vision problems, high blood pressure, high blood sugar, very slow heartbeat, muscle damage. or have pancreatitis.
You need to contact your treating doctor immediately if you have side effects, such as:
Severe headache, feeling dizzy, confused; Blurred vision, seeing flashes of light or "floating" in your vision; Excessive thirst or urinating several times a day; Feeling hungry; Nausea, vomiting a lot; Unexplained upper abdominal pain that radiates to the back, unexplained muscle pain or weakness; Fever, cough, chest pain, difficulty breathing; Very slow heartbeat or feeling like you might pass out.
3. Notes before using Alunbrig
You should not use Alunbrig if you are allergic to Brigatinib. To make sure Alunbrig is safe for you, you need to tell your doctor if you have ever:
Have lung disease or other problems respiratory problems; heart rate slows down; High blood pressure; Vision problems; Diabetes or glucose intolerance; Pancreatic problems; Liver or kidney disease (or if you are on dialysis). You may need to have a negative pregnancy test before you start treatment with Alunbrig. This is because the medicine can harm an unborn baby if the father or mother is being treated with this medicine.
For women, do not use Alunbrig if you are pregnant. Alunbrig can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using Alunbrig, use an effective form of non-hormonal birth control such as an intrauterine device (IUD). Avoid becoming pregnant for at least 4 months after your last dose. For men, use a condom or other birth control method if your partner could get pregnant. You need to continue using condoms for at least 3 months after your last dose of Alunbrig. Alunbrig may affect fertility or the ability to have children in men. However, it is important that men use birth control to prevent pregnancy because the drug can harm an unborn baby. You should not breast-feed while using Alunbrig and for at least 1 week after your last dose.
4. How should you use the medicine?
You need to use Alunbrig exactly as prescribed by the treating doctor. Also, be sure to re-read all directions on your medication label, medication guide, or leaflet. Your treating doctor may sometimes change the dosage depending on the specific condition and medical condition of the individual.
Alunbrig is usually taken once a day and it is not affected by food, so you can take it before or after eating. You should swallow the tablet whole and do not crush, chew, or break the tablet. If you vomit immediately after using Alunbrig, do not continue taking another dose to make up for it, but keep your regular schedule. Check the blood pressure of the person using the drug regularly. You should not stop using this medicine unless your doctor tells you to. Store Alunbrig at room temperature away from moisture and avoid direct sunlight.
5. Therapeutic dose of the drug Alunbrig
The usual adult therapeutic dose of Alunbrig for non-small cell lung cancer:
Initial dose: 90 mg orally once a day for the first 7 days Maintenance dose: If the starting dose is used loading during the first 7 days, increase the therapeutic dose to 180 mg orally once daily. Duration of treatment: Until disease progression or unacceptable toxicity. Use: Treatment of people with advanced or intolerant metastatic non-small cell lung cancer (ALK)-positive non-small cell lung cancer (NSCLC) who are intolerant to crizotinib. You need to use Alunbrig exactly as prescribed by your doctor. Also, you should follow all directions on your medication label and read all medication instructions or leaflets. If you miss a dose, you should skip the missed dose and continue with the next dose on schedule.
In case of drug overdose, it is necessary to immediately take the person using the drug overdose to medical facilities for timely and correct treatment.
6. What should be avoided when using drugs?
Grapefruit can interact with drugs and lead to unwanted side effects to the health of the user. Therefore, while being treated with Alunbrig you need to avoid using grapefruit products.
Also, this medicine may cause blurred vision and may decrease your reaction. You should avoid driving or hazardous activities until you have determined how the effects of this medicine will affect you.
7. Undesirable effects of the drug Alunbrig
The use of Alunbrig may cause signs of an allergic reaction such as skin rash, urticaria; shortness of breath; swelling of the face, lips, tongue, or throat. You should contact your treating doctor immediately if the following signs appear:
Lung problems including cough, shortness of breath, chest pain, fever; Vision problems such as blurred vision, double vision, increased sensitivity to light, seeing flashes of light or "floaters" in your vision; high blood pressure with other signs such as severe headache, pounding in the neck or ears, dizziness; High blood sugar test with accompanying symptoms such as extreme thirst, frequent urination, hunger, nausea, fruity breath, weakness, forgetfulness; heart problems such as a very slow heart rate, feeling like you might pass out; Muscle problems including unexplained muscle pain or weakness; Gastrointestinal diseases such as pancreatitis, upper stomach pain and radiating to the back, nausea, weight loss . Your cancer treatment with Alunbrig may be delayed or stopped altogether if you have certain side effects.
The above is not a complete list of side effects and other possible side effects. You need to contact your treating doctor for medical advice about unwanted effects that may be experienced when taking the drug.
8. Drug interactions Alunbrig
Sometimes it's not safe to take several medications at once. Some medicines can affect the blood levels of other medicines you take, which could increase unwanted effects or make them less effective.
Many drugs can interact with the drug Alunbrig . This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed above. You need to tell your doctor about all your current medicines and any medicines you start or stop using.
Patients should be careful to keep this medicine and all other medicines out of the reach of children and family pets. Never share your medication with someone else and use Alunbrig only as directed.
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