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Coenzyme Q10 is an active ingredient involved in many important body processes. Some diseases can reduce endogenous Coenzyme Q10. At this time, the body requires to supplement this active substance with external products. One of them is the drug Ticonet 30mg. So what is Ticonet drug?
1. What is Ticonet?
Each Ticonet 30mg softgel includes the following ingredients:
The main active ingredient is Ubidecarenone, also known as Coenzyme Q10, 30mg; Some excipients include soybean oil, palm oil, lecithin, partially hydrogenated soybean oil, white beeswax, gelatin, concentrated glycerin, D-sorbitol 70%, ethyl vanillin, titanium dioxide, purified water. Characteristics of drug identification Ticonet 30mg is a soft, oval, red capsule containing a red-yellow suspension inside.
Coenzyme Q10 is a fat-soluble quinone, synthesized in cells and involved in many processes such as:
Transport of electrons in the plasma membrane; Synthesis of adenosine triphosphate (ATP) in mitochondria; Phosphoryl - oxidation in the inner mitochondrial membranes and membranes of some other cells involved in the conservation of cellular energy; Redox carrier in the mitochondrial respiratory chain, between NADH dehydrogenase and succinate dehydrogenase of the cytochrome b-c1 system; Anti-oxidant and stabilizes cell membranes, prevents degradation of metabolites necessary for ATP synthesis; Removes free radicals produced by lipid peroxide. Coenzyme Q10 has properties similar to a vitamin because of its structural similarity to vitamin K. Deficiency of endogenous coenzyme Q10 has been reported in a number of conditions such as congestive heart failure, mitochondrial disease, and hypercholesterolemia. .
Oral Coenzyme Q10 supplements help restore physiological levels of endogenous Coenzyme Q10. In addition, patients with dyscholesterolemia undergo long-term treatment with HMG-CoA reductase inhibitors, thereby inhibiting endogenous cholesterol synthesis as well as coenzyme Q10 synthesis. Oral coenzyme Q10 supplementation is essential.
After taking Ticonet, the main active ingredient will be absorbed through the lymphatic system in the gastrointestinal tract, then distributed into different tissues, reaching high concentrations in liver, heart, kidney, lung, gland tissues. pancreas and lower in other organs. The half-life of coenzyme Q10 is approximately 34 hours.
2. What are the effects of Ticonet?
According to research, the drug Ticonet 30mg brings a number of effects as follows:
Support to maintain cardiovascular health; Support to prevent and reduce the frequency of migraine attacks associated with nausea, vomiting; Supports the body's antioxidant processes.
Thuốc Ticonet 30mg chỉ định sử dụng cho người từ 18 tuổi trở lên
3. Dosage of the drug Ticonet 30mg
Ticonet 30mg drug is indicated for use in people 18 years of age and older with dosage depending on the treatment purpose as follows:
Antioxidant support: Do not take more than 10 tablets per day (maximum dose is 300mg coenzyme Q10/ day); Cardiovascular: Dosage from 30-300mg of coenzyme Q10/day equivalent to 1-10 tablets; Migraine prevention: 150-300mg of coenzyme Q10 equivalent to 5-10 tablets per day. With effective migraine prevention, patients need to take the drug for at least 3 months to see a clear effect. Contraindicated use if the patient has a history or hypersensitivity to coenzyme Q10 or any other ingredient of the drug.
4. Note when using the drug Ticonet 30mg
Some issues need to be cautious when using Ticonet 30mg:
Patients with biliary obstruction and liver failure should be careful when taking Ticonet because of the risk of potential accumulation of coenzyme Q10; It has been reported that coenzyme Q10 can reduce the effects of warfarin, so people taking warfarin need to be aware of this and take appropriate monitoring measures; The metabolism of Coenzyme Q10 and cholesterol is similar. Therefore, some statin drugs such as lovastatin, simvastatin and pravastatin are known to reduce coenzyme Q10 levels in people taking them. Some cautions related to the excipients of Ticonet 30mg:
Note that people with a history of allergy to peanuts or soy should not use Ticonet; People with rare hereditary disorders of fructose intolerance should not use Ticonet 30mg because the ingredient contains sorbitol; Ticonet 30mg contains sunset yellow FCF, so it may increase the risk of an allergic reaction.
Tác dụng không mong muốn hiếm gặp của thuốc Ticonet 30mg là rối loạn tiêu hóa
5. Side effects and interactions of the drug Ticonet 30mg
Some rare unwanted effects of Ticonet 30mg medicine such as gastrointestinal disturbances (such as stomach discomfort), nausea, loss of appetite, diarrhea or skin rash.
The potential for interaction of Ticonet with other drugs has been recorded as follows:
Ticonet 30mg may increase the effect of diuretics, cardiac glycosides and nitrates; Ticonet increases the antioxidant effect of vitamin E; Ticonet 30mg may prolong the antihypertensive effect of enalapril and nitrendipine; Coenzyme Q10 has a synergistic effect with L-carnitine in metabolism and circulation; Ticonet may reduce the risk of developing cardiomyopathy with β-adrenergic blockers or inhibiting the anticoagulant effect of warfarin; Coenzyme Q10 reduces the toxicity of anthracycline antineoplastic agents. Some other notes of the drug Ticonet 30mg:
Ticonet does not affect the ability to drive and operate machines; Animal studies have not shown any effect of Ticonet 30mg on pregnancy. However, there are no studies performed in pregnant women regarding the teratogenic effects associated with coenzyme Q10. Therefore, to ensure safety, only Ticonet 30mg should be used in the first 3 months and must ensure that the benefits outweigh the risks; It is not known whether coenzyme Q10 is excreted in breast milk, however, women who are breastfeeding should only use Ticonet 30mg when absolutely necessary. Thus, the question "What is the effect of the drug ticonet?" Answered in the article. To use the drug safely and effectively, patients need to "take to heart" the doctor's notes and instructions when taking ticonet.
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