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Agifivit 200/1mg drug has 2 main ingredients, 200mg Iron (II) fumarate and 1mg folic acid, which are commonly used in the prevention and treatment of iron deficiency anemia, folic acid deficiency in many different subjects. However, the drug Agifivit can also bring some unwanted effects that make users feel uncomfortable.
1. What is Agifivit?
Agifivit is an iron supplement with the main ingredients being iron (II) fumarate and folic acid used in the treatment and prevention of iron deficiency anemia. In which iron fumarate is an easily absorbed form of organic iron for the human body, iron (II) also plays an important role in creating hemoglobin, myoglobin and cytochrome C respiratory enzyme. If iron (II) deficiency, red blood cells. cannot form, the process of O2 absorption and CO2 emission are severely affected.The remaining component is folic acid - a vitamin of group B. In the body, folic acid is reduced to tetrahydrofolate, which is a coenzyme of many metabolic processes including the synthesis of purine or pyrimidine nucleotides, thus affecting the DNA synthesis. In the presence of vitamin C, folic acid is converted to leucovorin, which is necessary for the synthesis of DNA and RNA.
It can be seen that folic acid is an indispensable factor in nucleoprotein synthesis and normal erythropoiesis, deficiency of folic acid causes megaloblastic anemia similar to anemia caused by vitamin B12 deficiency. In addition, the combination of folic acid with iron for use in pregnant women to prevent megaloblastic anemia has a better effect than when using a single substance.
2. What are the effects of Agifivit?
Agifivit can supplement nutrients for debilitated people, newly recovered from illness, after surgery or to enhance nutrition for pregnant women and children in the growth period. Agifivit is indicated in the following cases:
Treatment and prevention of iron deficiency anemia, iron supplementation; Subjects with increased blood-forming needs such as: pregnant women who are breastfeeding, women after surgery, nutritional deficiencies during menstruation, menstrual regulation; After trauma, surgery, gastrectomy, malnutrition syndrome, recovery period after serious illness; People whose daily diet does not have enough iron or folic acid.
3. Side effects of Agifivit
Agifivit can cause some unwanted effects such as:
Nausea, vomiting; Diarrhea; Allergies, rash, urticaria; Dizziness, headache. Agifivit is also contraindicated in the following cases:
Hypersensitivity to one of the drug's components; Patients with iron overload; Iron-contaminated tissue disease; Hemolytic anemia ; Polycythemia vera; The same caution should be exercised when taking the drug with a person with normal iron levels for a long time, stop taking the drug if it is not tolerated. Children under 12 years old do not take tablets, capsules, drops or syrup only. Avoid taking pills with tea that reduce iron absorption.
4. Treatment of Agifivit overdose and common drug interactions
An overdose of Agifivit can lead to symptoms such as abdominal pain, nausea, vomiting, bloody diarrhea, dehydration, acidosis, and shock with somnolence. The first treatment is immediate gastric lavage with milk (or carbonate solution) or the use of a chelator, most specifically deferoxamine. For shock and alkaline abnormalities, acidosis will be treated in the usual way, more severe, need to go to the hospital for intensive treatment and resuscitation.Agifivit has relatively many interactions with other drugs such as:
Reduces absorption of Penicillamin, Tetracycline, Levodopa, Methyldopa, Quinolones, thyroid hormones and poor mosquitoes if used together; If taken with antacids such as calcium carbonate, sodium carbonate and magnesium trisilicate, tea may reduce iron absorption; If folic acid is used to supplement folate deficiency, possibly caused by anticonvulsants, serum anticonvulsant concentrations may be reduced; Cotrimoxazole reduces the therapeutic effect of megaloblastic anemia of acid; Oral contraceptives reduce the metabolism of folate, causing a decrease in folate and vitamin B12. In summary, the drug Agifivit 200/1mg is often used in the prevention and treatment of anemia caused by iron deficiency, folic acid deficiency in many different subjects. Agifivit medicine can bring some unwanted effects that make users feel uncomfortable, so it is necessary to take the drug under the direction of a doctor to ensure safety.
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