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Question
Hello doctor,
I received a positive HBsAg II Cobas test result (1.05 COI) and a quantitative HBsAb test 148.5 IU/L. The doctor asked me, what does a positive HBsAg test mean?
Anonymous customer
Answer
Answered by Dr., Doctor Le Thi Huong - General Doctor - Outpatient Department, Vinmec Times City International Hospital.
Hello,
To the question "What does a positive HBsAg test mean?", the doctor would like to answer as follows:
HBsAg test is a decisive test to diagnose hepatitis B. To conclude that there is hepatitis B or not should have an HBsAg test but not an HBV-DNA test. If it's positive, you have hepatitis B. If it's negative, it means you don't have hepatitis B. HBsAg test has a qualitative or quantitative test: a qualitative test shows whether a patient has hepatitis B, while a quantitative test indicates a high or low antigen concentration, valuable for monitoring treatment. treat.
Anti-HBs is an anti-HBsAg antibody. Normally, after recovering from illness or after vaccination, if anti-HBs antibodies are present, there is immunity. Anti-HBs concentrations greater than 10 mUI/ml are considered protective.
If HBsAg is positive then you need to have the confirmation test again. After confirming that HBsAg is positive, biochemical and hematological tests should be done to evaluate liver function. You also need to do molecular biology tests such as HBV-DNA, HBV genotyping. The markers to be completed are: Quantification of HBsAg, Anti-HBs (HBsAb), HBeAg, Anti-HBe (HBeAb), Anti-HBc, Anti-HBcIgM. You should see an infectious hepatologist for a checkup.
If you still have questions about the HBsAg test, you can go to a hospital under Vinmec Health System for further examination and advice. Thank you for trusting and sending questions to Vinmec. Wishing you lots of health.
Best regards!
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