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What disease does Batonat treat? Batonat medicine 400mg of Phil Inter Pharma Co., Ltd.- Vietnam produced has the effect of supporting the treatment of liver diseases. The following article will provide information about the uses, as well as how to use Batonat 400.
1. What is Batonat 400?
Batonat 400 has the main ingredient is L-ornithine-L-aspartate, which belongs to the group of drugs known as biliary drugs, dissolve gallstones and protect the liver. Formulated in capsule form with strength, manufactured by Phil Inter Pharma Pharmaceutical Company, the drug is indicated for the treatment, support and maintenance of liver function in mild to moderate liver diseases such as acute hepatitis. hepatitis, chronic hepatitis, alcoholic hepatitis, fatty liver, and cirrhosis.
L-ornithine-L-aspartate is a chemical compound made up of the two amino acids aspartic acid and ornithine. Most of these amino acids are used as building materials to make proteins. But L-ornithine and L-aspartate are not used by the body to make proteins. Instead, it is absorbed, metabolized, and broken down by the body to provide aspartic acid and ornithine. L-ornithine-L-aspartate is most commonly used to decrease brain function in people with hepatic encephalopathy (advanced liver disease). This compound is also used in the treatment of cirrhosis and other diseases, but currently there is no scientific evidence to support these uses.
Absorption of Batonat: L - ornithine L - aspartate, after being taken orally, will move through the stomach through the digestive tract and be absorbed into the capillaries of the villi, located in the small intestine. Distribution Batonat: The drug travels through the circulation to the liver and then distributed throughout the body. Batonat drug metabolism: Drug metabolism takes place in the liver. The amino groups (NH2) and the nitrogen component, are converted to ammonia (NH3) and then combined with CO2 to form urea. High levels of L - ornithine L - aspartate are detected in the blood between 12 and 20 hours. Batonat drug excretion: The drug after metabolism is excreted in the urine and feces. The bioavailability of L - ornithine L - aspartate is about 82.2 ± 28%.
2. What disease does Batonat treat?
2.1. Pharmacodynamics of the drug Batonat L - ornithine L - aspartate compound is a double salt complex, different from the usual L - ornithine component, when taken into the body, this double salt complex will dissociate into The two amino acids are L - aspartate and L - ornithine. These are also two amino acids that are used as raw materials to participate in the urea cycle and the glutamine synthesis.
Single element L - ornithine acts as an activator of the enzymes carbamoyl phosphate synthetase and ornithine carbamyl transferase. This element is considered as the substrate for the urea synthesis cycle. It removes ammonia from the blood. The element L - aspartate, after forming citrulline, will enter the urea cycle and provide the second amino acid - an essential amino acid for the urea synthesis cycle in the liver. The job of L - aspartate is to stimulate the enzyme that synthesizes glutamine in the liver and leads to a decrease in ammonia levels.
In addition, two simple substances L - ornithine and L - aspartate also indirectly participate in ATP energy generation by activating the Krebs cycle to provide energy for urea synthesis and at the same time stimulate favor the operation of other functions of the liver, especially the function of liver parenchyma regeneration and fat metabolism. This is also an important function in the treatment of fatty liver and the treatment of hepatitis.
Many research reports show that on many patients using the drug, liver disease symptoms improved very well, liver enzyme index decreased rapidly, markedly improved obesity. Clinically, the patient eats better, the symptoms of digestive disorders are gone, and the facial skin is no longer yellow.
2.2. Contraindications of Batonat Drugs Patients with known allergy or hypersensitivity to any component of Batonat 400. Patients with severe renal impairment Patients with methanol poisoning, lactic acidosis or patients with deficiency Congenital G6PD enzyme. Use with caution in the elderly, pregnant women, lactating women and children.
2.3. Drug interactions If you use other drugs or over the counter products at the same time, the effects of L-Ornithine-L-Aspartate may change. This can increase your risk of side effects or keep your medicine from working properly. Tell your doctor about all medications, vitamins, and herbal supplements you are taking so he can help you prevent or manage drug interactions. Batonat 400 may interact with the following drugs and products:
Cyclosporin A Gemfibrozil Losartan Peginterferon Ribavirin Rifampicin Simeprevir Trazodone 2.4. Side effects of Batonat drugs Batonat drugs are quite benign, so there are almost no side effects. However, sometimes the drug still occurs some rare side effects such as:
Digestive disorders Mild allergic reactions Urticaria Nausea, vomiting Headache Joint pain Gastroenteritis
3. How to use the drug Batonat
Batonat 400mg drug is made in the form of soft capsules, should be taken directly with water, swallowed whole, do not break the tablet and absolutely do not chew or bite the tablet when taking it.
Patients should take the drug after meals and take Batonat 400mg with boiled water to cool.
4. Dosage of the drug Batonat
Adults: 1 to 2 tablets / time x 3 times / day, take the drug after meals, use continuously for 1 to 2 weeks. Maintenance dose: 1 tablet x 3 times daily for 4 to 5 weeks as directed by your physician. Note: Batonat 400mg dosage above is for reference only. The specific dose depends on the patient's condition and the progression of the disease. You do not arbitrarily buy and use drugs, you need to consult your doctor to get the right dosage.
Batonat 400mg drug produced by Phil Inter Pharma Co., Ltd. - Vietnam has the effect of supporting the treatment of liver diseases. To ensure the effectiveness of treatment and avoid side effects, patients need to take medicine according to prescription or consult a doctor, pharmacist for advice.
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