This is an automatically translated article.
Kitrampal belongs to the group of analgesics, antipyretics and anti-inflammatory drugs. This is a combination drug between 2 ingredients Tramadol hydrochloride and Paracetamol, usually indicated in cases of moderate to severe pain. What does Kitrampal do?1. What is Kitrampal?
Kitrampal medicine has the main ingredients including Tramadol and Paracetamol with the following pharmacodynamic effects:
Tramadol is a central analgesic with 2 mechanisms of action, the linkage of the parent substance and the active metabolite (M1). with the Mu-opioid receptor, mildly inhibits the reuptake of norepinephrine, serotonin. Paracetamol is also a central analgesic with the exact mechanism of analgesic action not yet clearly defined, but studies have shown that it has a synergistic effect with Tramadol to increase the drug's potency. Kitrampal medicine is usually indicated in the following cases:
Treatment of symptoms of runny nose, stuffy nose, cough, watery eyes, aches and pains caused by colds and flu. Support for the treatment of moderate and mild pain such as headache, menstrual pain, toothache, muscle and joint pain caused by movement, pain due to injury after an accident or playing sports. Kitrampal is contraindicated in the following cases:
Patients with hypersensitivity to any ingredient of Kitrampal. Pregnant and lactating women because there is not enough research on the safety of the drug in infants and young children. Patients with liver failure, renal failure or taking MAO for 2 weeks. Patients with heart, liver, lung, kidney related diseases, multiple anemias or G6PD deficiency. Not recommended for children under 12 years old. Use caution when using Kitrampal with the elderly, driving or operating machinery.
2. Dosage of Kitrampal:
Kitrampal is made in the form of oral capsules, can be used directly and is not affected by food. Depending on the subject and treatment goal, the dose of Kitrampal will be different, specifically as follows:
Adults and children over 12 years old: take up to 1-2 tablets each time 4-6 hours apart. and up to 8 tablets/day. Children under 12 years of age: The safety and effectiveness of Kitrampal with this medicine have not been studied. Elderly people over 65 years of age: there were no differences in efficacy or safety between this population and younger subjects. When using Kitrampal overdose, the patient may have symptoms of Tramadol or Paracetamol poisoning such as respiratory failure, coma, convulsions and death. Especially when taking very high doses Paracetamol can cause symptoms of hepatotoxicity, appearing 48-72 hours after taking the drug.
3. Kitrampal side effects:
In some patients when using Kitrampal, side effects may occur such as:
Side effects on the central nervous system often occur with common nausea, dizziness, dizziness, drowsiness. Weakness, fatigue. Headache, shivering. Abdominal pain, constipation, diarrhea, indigestion, flatulence, dry mouth, vomiting. Psychiatric disorders: anorexia, anxiety, confusion, agitation, insomnia, restlessness Itching, rash, increased sweating. Cardiovascular disorders: drop or increase in blood pressure. Vestibular disorders: tinnitus. Arrhythmia, palpitations, tachycardia.
4. Precautions when using Kitrampal:
Some general precautions when using Kitrampal include:
Be careful when using Kitrampal with SSRIs (serotonin reuptake inhibitors), TCAs (tricyclic compounds) or in pre-existing patients. history of convulsions because of the increased risk of convulsions. Caution is advised when using high doses of Tramadol with local anesthetics, anesthetics or alcohol because of the risk of respiratory depression. Care should be taken when using Kitrampal with central nervous system depressants such as opioids, anesthetics, anesthetics, hypnotics and sedatives. Kitrampal should be used with caution in patients with increased intracranial pressure, head trauma, and opiate addiction (because of the risk of relapse). Kitrampal should be used with caution in patients with chronic alcoholism because of the risk of hepatotoxicity. The use of Naloxone in the management of an overdose of Tramadol may increase the risk of convulsions. For patients with creatinine clearance less than 30 ml/min, a dose of no more than 2 tablets is recommended every 12 hours. Use caution when administering Kitrampal to patients with severe hepatic impairment. Do not use with other medicinal products containing Paracetamol or Tramadol.
5. Drug interactions with Kitrampal
Concomitant use of Kitrampal with MAO inhibitors or serotonin reuptake inhibitors may increase the risk of adverse events, including seizures and serotonin syndrome. Co-administration of Kitrampal with Carbamazepines may significantly increase the metabolism of the Tramadol component. The analgesic effect of Tramadol in the drug may be reduced in patients taking Carbamazepine. Taking Quinidine with tramadol might increase Tramadol levels. Co-administration of Kitrampal with warfarin may increase blood clotting time in some patients. Co-administration of Kitrampal with CYP2D6 inhibitors may limit the metabolism of Tramadol. Above are the uses, doses and notes when using Kitrampal medicine. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Kitrampal exactly as directed by your doctor.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
