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Cerepril belongs to the group of cardiovascular drugs with the main ingredient Enalapril maleate with a strength of 5mg. The drug is commonly prescribed in the treatment of cardiovascular diseases. To learn more about the use and safe use of the drug, please read the article below.
1. Uses of the drug Cerepril 5mg
Thanks to the ingredient Enalapril maleate, Cerepril is indicated in the treatment of cardiovascular diseases such as:
Treatment of mild to severe idiopathic hypertension. High blood pressure caused by kidney disease. Treatment of hypertension co-existing with diabetes. The drug works to improve heart failure such as: prolonging life, preventing the development of heart failure and reducing the number of heart attacks. Treatment and prevention of congestive heart failure. On the other hand, in order to ensure the safety of the patient's health, the drug will not be prescribed in the following cases:
The patient is allergic to the ingredient Enalapril maleate or any of the excipients of the drug. Patients experienced angioedema at the beginning of treatment as with ACE inhibitors in general. The drug is contraindicated in patients with bilateral renal artery stenosis or renal artery stenosis in patients with only one kidney. Patients with aortic stenosis, and severe obstructive cardiomyopathy.
2. Dosage and usage of Cerepril 5mg
2.1. Cerepril is made in the form of tablets, so it is recommended to take it orally. Patients are advised to take the tablets whole, do not break or crush them. Take the medicine with plenty of filtered or boiled water, avoid using alcoholic beverages or juices.
Patients can take Cerepril before or after meals, food does not change the bioavailability of the drug.
2.2. Dosage The dosage of Cerepril drug depends on the purpose of treatment of the disease, the state of impaired kidney function and the patient's physical condition. Each patient will have their own prescription, absolutely do not share a prescription with others or change the dose without indication. The following is a reference dose of Cerepril as follows:
Treatment of primary hypertension has an initial dose of 5mg, the dose can be increased depending on the degree of hypertension, the maintenance dose is determined after 2-4 hours. week of treatment. The daily dose is 10-40 mg, taken once a day or in two divided doses. Maximum dose 40 mg/day. In case of renal failure, the dose will be adjusted according to the creatinine clearance: When the creatinine clearance is 30 - 80 ml/min, the dose is 5 - 10 mg/day. When creatinine clearance 10-30 ml/min, dose 2.5-5 mg/day. Treatment of heart failure will be combined with digitalis drugs and diuretics. Thus, an initial dose of 2.5 mg, which can be gradually increased to a therapeutic dose, must be done under careful monitoring.
3. Side effects of the drug Cerepril 5mg
Cerepril drug causes side effects during use. When these symptoms arise, it is important to notify your doctor for prompt treatment. Patients should notify their doctor for timely diagnosis and treatment instructions, and do not arbitrarily use other drugs to treat side effects of the drug.
Some of the side effects are: Anemia, aplastic anemia and hemolytic anemia, neutropenia, decreased hemoglobin, decreased haematocrit, thrombocytopenia, agranulocytosis, bone marrow suppression, decreased total thrombocythemia, autoimmune disease, blurred vision, cough, shortness of breath, runny nose, sore throat, rhinitis, allergic alveolitis/eosinophilic pneumonia, nausea, diarrhea, abdominal pain, taste changes, intestinal obstruction, pancreatitis, vomiting, dyspepsia, constipation, loss of appetite, stomach irritation, dysphagia, stomach ulcers, mouth sores, liver failure, hepatitis, cholestasis (including jaundice)....
These are not all side effects of Cerepril. During treatment with this medicine, if the patient experiences any unusual symptoms, they should notify the doctor.
4. Cerepril 5mg . drug interactions
Drug interactions occur that may increase the side effects of Cerepril or reduce the effectiveness of treatment. There have been reports of drug interactions between Cerepril and some drugs such as:
Combining enalapril with some other vasodilators and anesthetics will lead to severe hypotension. The combination of enalapril and a diuretic will cause excessive hypotension. Do not take Cerepril with drugs that cause renin release. Concomitant use of enalapril with drugs that increase serum potassium leads to a high risk of increased serum potassium. The combination of enalapril with lithium is not recommended, which may increase blood levels leading to lithium toxicity. Cerepril 5mg may cause interactions with certain other medications. Therefore, to minimize health risks, patients should make a list of all medications they are taking (including prescription, over-the-counter, herbal and dietary supplements) and show it to their doctor. advise.
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