Waking up early in the morning may reduce breast cancer risk

This is an automatically translated article.

The article was written by doctors of Internal Oncology - Radiation Oncology Center, Vinmec Times City International Hospital
Living at the right scientific time and maintaining it for a long time not only keeps the body healthy but also repels the risk of cancer. Sleeping in, sleeping more than 8 hours a day is one of the factors that contribute to the increased incidence of breast cancer.

1. Waking up early in the morning will have a lower risk of breast cancer

A large database study has shown that women who wake up early in the morning may have a lower risk of breast cancer. In a study recently published in Medical news update, researchers used analytical data from 180,216 women from the UK Biobank and 228,951 women from the Breast Cancer Society. From there, they found solid evidence that getting up early in the morning has a reduced effect on breast cancer risk.
The study also found evidence that; that sleeping more than 7-8 hours per night may have the opposite effect of reducing breast cancer risk. However, the researchers also stress that these effects are small, compared with other risk factors for breast cancer, such as obesity, alcohol consumption and smoking.

2. Focus on characteristics rather than mutable factors

Although there have been many published studies in the past showing an association with an increased risk of breast cancer in people who work night shifts. However, few studies have focused on characteristics that individuals themselves find difficult to change, such as getting up early in the morning or staying up late at night for example.
In this study, the researchers performed two analyses. In the first analysis, a multivariable regression analysis was performed on UK Biobank data to find associations between breast cancer and early morning or late night awakening, sleep duration and symptoms of loss of sleep. sleep of the participants.
The second analysis was a randomized analysis, performed on UK Biobank data and two Breast Cancer Association (BCAC) data samples. The researchers used genetic data on the participants' circadian clocks, sleep duration and insomnia to look for links with breast cancer.
The results of the study show that getting up early in the morning is associated with a lower risk. Specifically, multivariate regression analysis of UK Biobank data showed that women who wake up early in the morning have a 1% lower risk of breast cancer than women who stay up late in the evening.
A factor that affects less than 1% of a woman's risk of breast cancer means it affects less than 10 people in 1,000 women.
Therefore, the first analysis found that there was little evidence to link sleep duration, insomnia symptoms with breast cancer.
The second UK analysis added support to these results, as well as analysis of two samples of Breast Cancer Society data, which showed only a small negative effect of increased breast cancer risk. Sleep duration on breast cancer risk.

3. Evidence for a cause-and-effect relationship

The authors conclude that these findings provide evidence of circadian clock causality on breast cancer risk.
As Eva Schernhammer, professor of epidemiology at the University of Vienna, points out that this study identifies the need for further studies to show how to reduce stress on our circadian clock.
In addition, she says that this research can also help to align working hours with each individual's biological clock.
Dr Luca Magnani, a senior research fellow in surgery and oncology at Imperial College London UK, also commented on the findings. He describes the study as interesting, in which researchers have identified an association between genetic variation (which is associated with sleep characteristics) and breast cancer risk, although the effect is very small. .
He also points out that these results show no link between modifying sleep habits and reducing breast cancer risk.

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Source: medical news today