Uses of Zirgan

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Zirgan is an antiviral drug that slows the growth and spread of cytomegalovirus (CMV). Zirgan eye drops are used to treat keratitis caused by the herpes simplex virus in adults and children 2 years of age and older.

1. What effect does Zirgan have?

Zirgan is an Italian eye drop gel produced in the form of a 5g tube, whose active ingredient is ganciclovir. The drug is active against the herpes simplex virus as well as some adenoviruses by inhibiting viral DNA synthesis. Zirgan is used to treat keratitis caused by the herpes simplex virus. The drug is usually used five times a day until the condition improves, then switched to three times a day, a course of treatment usually no longer than three weeks. The medicine may cause eye discomfort, such as burning and tingling sensations. Do not use Zirgan drug for patients with hypersensitivity to the components of the drug and children under 2 years of age.

2. Dosage and usage of Zirgan

2.1. Dosage

Dosage will vary depending on the patient's condition. To know the most accurate dose, patients should visit specialized clinics to be prescribed by a doctor. The following is a reference dose of Zirgan:
Usual Dose in Adult Patients with Herpes Simplex Keratitis : Instill 1 drop in the affected eye 5 times a day (approximately every 3 hours) until the sore is in the affected eye. cornea healed, then instill 1 drop 3 times a day for 7 days. Usual Pediatric Dose for Children 2 Years of Age and Older with Herpes Simplex Keratitis: Instill 1 drop in the affected eye 5 times a day (approximately every 3 hours) until the corneal ulcer heals, then instill 1 drop 3 times a day for 7 days.

2.2. How to use

Zirgan eye drop gel is usually applied about every 3 hours, up to 5 times per day. When the eye wound heals, the gel is usually applied 3 times daily for 7 days. How to use Zirgan eye drops gel as follows:
Wash your hands before using the medicine. Tilt your head back slightly and pull your lower eyelid down to create a small pocket. Hold the dropper above the eye with the tip facing down. Look up and at the same time instill the solution into the eyes, closing the eyes for 1 or 2 minutes. Repeat the action above according to the dose prescribed by the doctor. Gently press your finger against the inner corner of the eye (near the nose) for about 1 minute to keep the liquid from flowing into the tear duct. If using more than one drop in the same eye, wait about 5 minutes before applying the next drop. If the patient must use another type of eye drop, wait at least 5 minutes in between before using another medication. Do not let the dropper tip come into contact with any surface, including eyes or hands. Contaminated droppers can cause eye infections, leading to vision loss or serious eye damage. Store Zirgan at room temperature, away from moisture and heat. Keep the eyedropper bottle tightly closed when not in use.

3. What are the side effects of Zirgan?

Common Zirgan side effects can include: blurred vision, eye irritation, redness, watery eyes, sensitivity to light. Call your doctor right away if you have any of the following: vision changes, eye pain, burning, red or watery eyes, burning sensation in your eyes. In case there are signs of an allergic reaction such as hives, difficulty breathing, swelling of the face, lips, tongue or throat, the patient should immediately seek medical attention for timely treatment.

4. What are the precautions when using Zirgan?

When using Zirgan, patients should note the following:
Before using the drug, tell your doctor or pharmacist if you are allergic to ganciclovir, valganciclovir or acyclovir. To make sure it is safe to use Zirgan, tell your doctor if you have an infection in any part of your body (other than your eyes) or low blood platelets (easy bruising or bleeding). ). Zirgan may cause blurred vision. Avoid driving or operating machinery while taking this medicine. Wash your hands often to prevent the spread of infection. Do not use other eye drops unless your doctor tells you to. Do not wear contact lenses while using Zirgan. After an eye sore heals, consult your doctor before using contact lenses, as wearing contact lenses can increase your risk of recurrent herpes infections or recurrent eye ulcers. Zirgan gel should not be given to children under 2 years of age. If the disease continues to progress after being treated with Zirgan, the patient should be re-examined for treatment adjustment. Pregnancy: It is not known whether Zirgan will harm an unborn baby. Ganciclovir may decrease sperm count and may affect male fertility. The manufacturer recommends that caution should be exercised when using eye drops in pregnant women. Lactation: It is not known whether ganciclovir passes into breast milk or will harm a nursing baby. Before using Zirgan, it is necessary to inform the doctor if the patient is breast-feeding. Above is information about the uses, dosage, usage and notes when using Zirgan medicine. Patients should not self-medicate, but should consult a doctor or pharmacist before taking.

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