Uses of Zestril

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Zestril 10mg can be effective when used to treat patients with heart failure or people with hypertension. Are there things to pay attention to when using Zestril to increase its effectiveness? Please read the article below to get more useful information.

1. Composition of the drug Zestril

Zestril is available in 2 dosage forms, 5 mg and 10 mg. In which we are popular is the drug is made in the form of tablets with a dose of 10 mg. In a 10 mg tablet, there are 10 mg of Lisinopril and other excipients to balance and create the required concentration.

2. What diseases does Zestril 10mg treat?

The use of Zestril is largely due to the Lisinopril component. This is a substance in the group capable of causing ACE inhibitors to help lower blood pressure and treat patients with heart failure.
When using Zestril to help lower blood pressure, the drug will form Angiotensin II. At the same time, the body secretes Aldosterone on the adrenal glands to dilate blood vessels and at the same time reduce pressure on the vessel walls. The good blood circulation in the arterial wall will reduce the pressure. Thanks to this principle, blood pressure is effectively reduced.
For patients with heart failure, Zestril has the ability to increase cardiac output. Afterload preload problems are reduced to an acceptable level without the heart suffering adverse effects or arrhythmias. Long-term use of this drug will prevent the threat of left ventricular hypertrophy. Or who has suffered will reduce the danger.
Thanks to the 2 effects of lowering blood pressure and treating people with heart failure, Zestril can be used in combination or alone. The decision to use Zestril alone or to combine it with other drugs will be made by the doctor and advised to the patient.

3. Divide the dose used for each subject

First, it is important to remember that Zestril 10 mg belongs to the prescription group and only buys it at the pharmacy if it is prescribed by a doctor. Therefore, you absolutely do not buy or use the drug yourself or do not determine the dose without consulting your doctor. The usual dose is once a day. In each patient, different medical conditions, the dose of the drug is also changed to suit the body's needs.
3.1 Dosage for people who need to lower blood pressure Newly prescribed patients will be given the first dose of 10 mg / day. Patients with the presence of the highly active chemical Renin - Angiotensin - Aldosteron will receive a lower initial dose of only about 2.5 to 5 mg/day. After that will maintain the use of 20 mg / day.
During the time of taking the doctor can change the dose if necessary. First increase to 20 - 20 mg/day then 80 mg/day. Most patients will make sure not to exceed doses above 80 mg/day.
If the patient is using diuretics, Zestril should not be used in combination. Please stop taking the drug for 2-3 then should use Zestril. Patients with poor or impaired renal function should not be given high doses. The dose for this patient will be reduced by the doctor to less than dangerously low.
Children who can take the drug need to be over 6 years old. Limits 6 - 16 years old will calculate the full dose based on the child's weight. Children under 50 kg will be given the first dose of 2.5 mg and over 50 is 20 mg / day. Children under 50 kg per day should not exceed 40 mg/day. Based on the above dosage and usage, a weight-based dose of 0.61 mg/kg can be calculated.
Children often have not yet fully developed health, so if their organs are damaged, they will have long-term effects. Therefore, do not exceed doses above 40 mg per day. If the child shows signs of impaired renal function, the dose should be re-evaluated accordingly.
3.2 Dose for Heart Failure Patients with heart failure will have a starting dose ranging from 2.5 to 10 mg/day. Thereafter, the maintenance dose based on condition will be increased from 5 to 20 mg/day. After 2 weeks of examination and review, your doctor will advise you to increase or decrease the dose so that it does not exceed 35 mg / day.
If the prescribed patient has an acute myocardial infarction, start with a dose of 5mg. After 24 hours continue to use the dose of 5 mg and after 48 hours increase to 10 mg, maintain until the doctor adjusts or requests to stop taking the drug.
In subjects used for low systolic blood pressure (less than 120 mmHg) a dose of 2.5 mg should be given. When over the first time will maintain oral 10 mg / day. The process of using drugs should be considered and monitored to control health in a timely manner. If there are signs of hypotension, notify the doctor to adjust the dose.
Usually, when a patient takes medication and has low blood pressure, the doctor will ask to temporarily take 2.5 mg or temporarily stop taking the drug to stabilize the blood pressure. For people with kidney disease such as diabetes, do not take more than 20 mg / day. Detailed dosage instructions will be detailed by your doctor.
Elderly people, people with impaired kidney function do not have a fixed dose. Depending on the state, the doctor will give advice suitable for health. If you have recently undergone or have had a kidney transplant, you should also tell your doctor.
All dosages are for reference only, not advice for users. You should not rely on these dosages to buy and use drugs on your own. Inform your doctor about the medication you are taking and your medical history and health problems so that he can be examined and accurately determine the need for medication.
When taking the drug, drink a full glass of water to create a sufficient environment for the metabolism. At the same time, you need to make sure that you take the correct dose and dose as prescribed by your doctor.

4. Contraindications to the use of Zestril

Currently because it is a prescription drug, few patients will know about it. However, based on published research literature, Zestril 10mg is not indicated for use in patients with signs of allergy to lisinopril. Some patients develop an allergic reaction after using the drug, which will be discontinued and an allergy history recorded.
People with angioedema are in the object of contraindications to using the drug. In addition, pregnant women or those who are breastfeeding should not use Zestril at all. In addition, there are many other contraindications that have not been concluded but are still informed by prescription for your reference at the time of purchase.

5. What are the side effects of Zestril?

Diarrhea, kidney dysfunction, nausea, dizziness, low blood pressure.... are side effects that patients may experience when taking Zestril.
Besides, some patients have experienced problems such as loss of sharpness, unstable taste, rhinitis, allergic rash, vascular edema, especially in parts such as the face and nose. .... Rare manifestations are potentially more dangerous.
You need to pay attention if you find that your memory is impaired, your sense of smell is disturbed, your mouth is dry.. Some symptoms that need to be tested to be discovered are also dangerous such as increased blood urea, acute kidney failure, female. breast cancer ..
More dangerous, side effects can affect the bone marrow, reduce platelets, white blood cells causing bronchospasm ... Other problems can affect the liver causing poisoning toxic and lead to negative psychological manifestations.

6. Drug interactions, precautions and storage

Currently, Zestril drug has the ability to interact with diuretics, blood pressure stabilizers, anesthetics, drugs for psychological disorders.... It is possible to see the interaction of Zestril with other drugs. This should be given great attention. Because patients with high blood pressure or heart disease will have problems with the above diseases. Doctors need patients to provide enough information about their medical history and medications to be able to prescribe the safest and most appropriate medication for their health.
What disease does Zestril 10 mg treat? According to current analysis, the two main functions of the drug are to treat heart disease and to help reduce blood pressure for patients. Also, if you need more information about your medicine, ask your pharmacist or treating doctor for support and help.

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