Uses of Zebacef 300mg

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1. Uses of Zebacef 300mg

The Cefdinir component in Zebacef is a semi-synthetic broad-spectrum antibiotic. Zebacef belongs to the group of 3rd generation Cephalosporins. It works by inhibiting bacterial cell wall synthesis.
Due to its stability to some Beta-lactamase enzymes, Cefinir is sensitive to many strains that are already resistant to penicillins and some cephalosporins. This ingredient is active against both gram (-) and (+) aerobic bacteria.
The drug is effective in infections with varying degrees of mild to moderate.
Treatment of community-acquired pneumonia and exacerbations of chronic bronchitis. Treatment of pharyngitis, tonsillitis. Uncomplicated gonorrhea Treatment of infections in obstetrics and gynecology Skin and soft tissue infections Prophylaxis of post-operative infections Urinary and genitourinary infections Although the drug is effective in many infections, However, Zebacef is contraindicated in the following cases:
Patients with hypersensitivity to Cefdinir components or any of the excipients in the drug. Patients allergic to beta-lactam antibiotics. Use with caution in children under 12 years of age

2. Usage and dosage of Zebacef 300mg

2.1. How to use Zebacef 300mg is made in the form of tablets, so patients are recommended to take it orally. When taking the medicine, it should be taken with a glass of filtered or boiled water. Do not take the drug with fruit juices or alcoholic beverages to avoid affecting the drug's pharmacokinetics.
2.2. Dosage For each different treatment purpose, the doctor will adjust the dose differently. Specifically:
Treatment of community-acquired pneumonia, take 2 times a day, 1 tablet each time. The time between 2 doses is 12 hours apart. The course of treatment lasted 10 days. Treatment of chronic bronchitis, acute sinusitis, tonsillitis: 2 tablets/time/day for 10 days. Your doctor may prescribe 1 tablet every 12 hours for 5 to 10 days. Treatment of uncomplicated skin and soft tissue infections: 1 tablet every 12 hours, for 10 days Zebacef 300mg drug does not require dose adjustment for patients with liver failure and the elderly. However, patients with renal impairment with creatinine clearance < 30 ml/min take 1 tablet once/day. Patients on hemodialysis: Start with 1 tablet every 48 hours, followed by 1 tablet at the end of each dialysis session.
Use of insufficient dose of Zebacef significantly affects the activity of the drug. This condition can cause the drug to decrease the mechanism of action, leading to not completely treating the symptoms of the disease.
If the patient forgets to take a dose of Zebacef, take it as soon as he remembers. If it is almost time for the next dose, skip the missed dose and take the next dose as scheduled.
Currently, no case of drug overdose has been recorded. However, patients should not be subjective but should follow the doctor's dose to avoid poisoning with beta-lactam antibiotics. During the course of taking the drug, if you experience symptoms such as: nausea, vomiting, epigastric pain, diarrhea and convulsions... suspected of overdose, you should notify your doctor for timely treatment.

3. Zebacef 300mg . side effects

Despite carefully weighing the benefits and risks that Zebacef 300mg brings to patients, the drug can still cause some unwanted side effects.
Common side effects tend to go away on their own after a few days or weeks. Meanwhile, serious reactions can develop and threaten the health of the user. With serious side effects, the doctor may order treatment to improve the situation.
Common side effects such as: Diarrhea, nausea, abdominal pain, headache, vaginitis, Monilia vaginitis in women... Less common side effects: Abnormal stools, indigestion, constipation, dry mouth, flatulence, vomiting, loss of appetite, pseudomembranous colitis, dizziness, insomnia, somnolence.

4. Drug interactions Zebacef 300mg

Drug interactions can increase the side effects of Zebacef 300mg or reduce the effectiveness of treatment. To avoid this, the patient should make a list of all the medications they are taking (including prescription, nonprescription, herbal and dietary supplements) and show it to their doctor or pharmacist. Some drugs can interact with Zebacef such as:
The combination of Cefdinir with aluminum or magnesium-containing antacids, iron supplements and iron-fortified foods will reduce the effectiveness of Zebacef. . Therefore, these drugs should not be combined. If you have to drink together, you should take at least 2 hours apart. Concomitant use of Zebacef with Probenecid will increase AUC, increase Cmax, prolong the half-life. False positive for ketones in urine when tested using Nitroprusside, but not in people using nitroferricyanide.

5. Precautions while using Zebacef 300mg

Prolonged use of Cefdinir may cause overgrowth of Clostridium difficile. Caution should be exercised in case of history of colitis, impaired renal function in the elderly, history of allergy to penicillin. Do not use with any other preparations containing Cefdinir. For pregnant women, use the drug only when absolutely necessary. In the case of mandatory use, it is necessary to weigh the benefits that outweigh the risks that the drug brings. Pregnant women should consult a doctor before use to avoid affecting the health of the fetus and baby. People who frequently drive and operate machinery should use caution when using Zebacef. Because the drug can cause side effects such as headache, dizziness... Above is useful information about Zebacef 300mg drug line as well as its use. Hopefully, it has helped readers to use drugs safely and effectively.

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