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Xilavic 1000 is a drug commonly used in the treatment of infections caused by susceptible strains. To know how the drug works, how to use it, please refer to the information in the article below.
1. What is Xilavic 1000? What is the effect?
Xilavic 1000 is a drug made up of two main ingredients, including Amoxicillin (as Amoxicillin trihydrate) 875mg and Clavulanic Acid (as Potassium Clavulanate) 125mg.In which, Amoxicillin is an active ingredient in the Penicillin group of antibiotics, which works by killing and preventing the growth of bacteria. As a result, Amoxicillin not only brings the ability to kill bacteria but also helps eliminate the root cause of the disease. This is also an active substance that is usually stable in acidic environments and has a broader effect than benzylpenicillin against Gram (-) bacilli.
With clavulanic acid, this is a broad-spectrum antibiotic, which will be effective against many types of bacteria, including both Gram-positive and Gram-negative bacteria. However, due to their relatively weak bacteriostatic activity as well as the ability to prevent Amoxicillin from being destroyed by bacterial beta lactamases. From here, clavulanic acid is often combined with Amoxicillin to provide optimal bactericidal ability, preventing drug resistance when used long-term in the treatment of infectious diseases that are resistant to Amoxicillin.
2. Indications and contraindications
2.1. Indications Xilavic 1000 is indicated for use in the following cases:
Patients with upper and lower respiratory tract infections including pneumonia, otitis media, acute sinusitis, acute severe chronic bronchitis. Patients with skin and soft tissue inflammation. Patients with nephritis and lower urinary tract. 2.2. Contraindications Patients with a history of allergy to penicillins, patients with a history of cholestatic jaundice or liver failure. Patients with cross-allergy to cephalosporins, infectious mononucleosis or lymphoid leukemia.
3. Dosage and how to use Xilavic 1000
You can refer to the dosage and use of Xilavic 1000 as follows:
Usual dose: From 250 - 500mg calculated according to Amoxicillin, taken every 8 hours. Children under 10kg body weight: Use dose from 125 to 250mg (according to Amoxicillin), every 8 hours. Children under 20kg body weight: Use at a dose of 20-40 mg/kg daily, every 8 hours. Infants and children under 3 months of age: At this age, because the kidneys are not fully developed, it will affect the elimination of drugs. According to experts, the recommended dose of Xilavic 1000 is 30mg/kg/day (according to Amoxicillin) divided into doses 12 hours apart.
4. Side effects
During the use of Xilavic 1000, side effects are uncommon and only appear transient. Typical include:
Diarrhea, nausea, vomiting, itchy skin, rash, urticaria. Vaginitis, vaginal itching. Abdominal pain, bloating, headache.
5. Drug interactions
Xilavic 100 0 has the potential to interact with some drugs such as Allopurinol. Probenecid, anticoagulants, oral contraceptives. Therefore, you need to inform your doctor when you are using these drugs. Usually, your doctor will order either medication to be spaced apart or to be discontinued.
6. Some notes when using
You should take into account the possibility of a fungal or bacterial re-infection during the course of taking the drug. If reinfection occurs (primarily caused by Pseudomonas or Candida), the patient should discontinue the drug and institute appropriate therapeutic measures. Although Xilavic 1000 is one of the penicillin group antibiotics with low toxicity. However, you should still regularly check your kidney, liver and hematopoietic function during treatment with this medicine. Xilavic 1000 should be used with caution in patients with mononucleosis because of the potential for severe, sometimes fatal, hypersensitivity reactions. Above is some information about Xilavic 1000 that readers can refer to. When using the drug, patients should follow the dosage prescribed by the doctor to ensure the best treatment effect.
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