Uses of Wonlicla

This is an automatically translated article.

1. What is Wonlicla?

What is Wonlicla drug? The main ingredient in Wonlicla is Gliclazide which is a hypoglycemic sulfamide, an oral antidiabetic drug. Gliclazide is distinguished from other sulfonylureas by the presence of a nitrogenous heterocycle.
The hypoglycemic effect of Gliclazide is based on the stimulation of insulin secretion from the beta cells of the islets of Langerhans. In patients with type 2 diabetes, gliclazide restored early peak insulin secretion, in the presence of glucose, and increased second-phase insulin secretion. In addition, Gliclazide is known to have independent vascular properties by two mechanisms: One is partial inhibition of platelet aggregation and adhesion to the vessel wall, the other is an effect on fibrinolytic activity. in the vessel wall. The Gliclazide molecule is absorbed from the gastrointestinal tract and metabolized by the liver to metabolites without significant hypoglycemic activity.

2. Uses of the drug Wonlicla

Thanks to the ingredient Gliclazide, Wonlicla is effective in the treatment of non-insulin dependent diabetes.
On the other hand, the drug will not be effective and negatively affect health in the following cases:
Diabetes in children Diabetes has been complicated in the stages of ketosis and acidosis. Women in pregnancy Patients with hypersensitivity to any ingredient of the drug Diabetic patients undergoing surgery, after trauma or infection. People with coma and pre-coma due to diabetes. Patients with severe renal or hepatic failure

3. Dosage and usage

3.1. How to use Wonlicla drug is made in the form of tablets, so it should be guided for oral use. The drug is taken as a single dose in the morning. When taking, you take the tablet whole, do not break or crush it.
The action of the drug will last from 12 - 24 hours.
3.2. Dosage The starting dose of the drug is 30 mg / time. If this dose is effective in controlling blood glucose, it will be considered as a maintenance dose. In case blood glucose is not controlled, the dose will be gradually increased to 60 mg, 90 mg, 120 mg/day in increments. The interval between doses should be increased at least once a month. In case of overdose of Wonlicla, patients may experience symptoms of hypoglycaemia. In this case, the patient will be prescribed gastric lavage and correction of hypoglycemia with appropriate measures along with continuous monitoring of the patient's blood glucose status until the effects of the drug have subsided. are excluded.
Drugs will only be most effective when used in full doses. If you accidentally forget to take a dose, take it as soon as you remember. If the missed dose is almost time for the next dose, skip the missed dose. Absolutely do not arbitrarily double the dose will lead to an overdose.

4. Drug interactions

When using Wonlicla drug in combination with some other drugs, it may lead to an interaction, that is, a decrease in the effect of the drug or an increase in side effects. Therefore, in order to use the drug safely, the patient needs to inform the doctor of all the drugs he is taking. From there, the doctor will consider adjusting the dosage between drugs or replacing drugs (if necessary).
Some drugs may interact with Wonlicla as follows:
Gliclazide with drugs known to alter diabetes status or increase its effects. Phenylbutazone drugs, salicylates, sulfonamides, coumarin derivatives, MAOIs, β-adrenergic blocking agents, tetracyclines, chloramphenicol, clofibrat, disopyramide, miconazole (oral) and cimetidine. Oral contraceptives, thiazide diuretics, phenothiazine derivatives, thyroid hormones and laxative abuse.

5. Side effects of the drug Wonlicla

Wonlicla drug causes side effects during use. When these symptoms arise, it is important to notify your doctor for prompt treatment. Patients should notify their doctor for timely diagnosis and treatment instructions, note that do not arbitrarily use other drugs to treat side effects of Wonlicla drug.
Side effects on digestion such as: nausea, vomiting, belching, loss of appetite, diarrhea, increased appetite... Allergic reactions such as: Skin rash and itching, photosensitivity... Effects to liver function: increased liver enzymes, hepatitis, cholestatic jaundice, leukopenia, thrombocytopenia, aplastic anemia,... Common side effects tend to go away on their own after a few days or some week. Meanwhile, serious reactions can develop and threaten the health of the user. With serious side effects, the doctor may order treatment to improve the situation.

6. Be careful when using Wonlicla

Caution when using Wonlicla drug in the following cases:
Sulfonylurea is not allowed to be prescribed in the treatment of type 1 diabetes. When treating type 2 diabetes, it is contraindicated to prescribe for subjects. : diabetes mellitus in the stage of ketoacidosis and severe infection, trauma or other serious condition for which sulfonylurea drugs cannot control hyperglycemia. Low blood sugar while driving can lead to serious dangers. Therefore, when you notice signs of low blood sugar, you need to stop driving immediately and quickly add sugar. Avoid giving this medicine to women who are breastfeeding, as sulfonylureas may pass into breast milk. Carefully read the instructions for storage of the drug on the box and read the instruction sheet for the drug Wonlicla Before using, check the expiry date of the medicine. When not in use, the drug should be collected and disposed of according to the instructions of the manufacturer or those in charge of the medical field. Store the medicine in a dry place, avoid direct exposure to sunlight or high temperature, it can convert the ingredients in the medicine. Above is information about uses, dosage and precautions when using Wonlicla. To ensure safety for health and maximize the effectiveness of treatment, patients need to use Wonlicla exactly as directed by their doctor. Note, Wonlicla is a prescription drug, and patients absolutely cannot use it without a prescription from a specialist.
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