This is an automatically translated article.
Vosevi is an antiviral combination drug that includes sofosbuvir, velpatasvir and voxilaprevir. It is used to treat chronic hepatitis C in adults. To learn detailed information about the drug Vosevi, follow the article below.
1. What is Vosevi?
Ingredients sofosbuvir, velpatasvir and voxilaprevir in Vosevi are antiviral drugs, with a strength of 400 mg - 100 mg - 100 mg. The drug is prepared in the form of tablets, packaged in a box of 28 tablets.
Mechanism of Vosevi: The antiviral drugs present in Vosevi work by stopping the hepatitis C virus (HCV) from multiplying, reducing the amount of hepatitis C virus in the body, helping the immune system fight off infection. infection, helping the liver to recover.
2. What are the effects of Vosevi?
Vosevi is used to treat chronic hepatitis C in adults.
Vosevi is sometimes used in people with HIV, but not as a treatment for HIV/AIDS.
3. Dosage and usage of Vosevi
Dosage:
Usual adult dose for chronic hepatitis C: 1 tablet x 1 time/day, for 12 weeks. How to use:
Read the instructions for using Vosevi carefully before using. Vosevi is taken by mouth, with food, usually once a day. It works best when the amount of medicine in the body is kept constant, so Vosevi should be taken at the same time each day. Take the medicine for the full time as prescribed, even if symptoms go away. Stopping the medication early may cause symptoms to return.
4. Contraindications of the drug Vosevi
Do not use Vosevi if:
Are allergic to sofosbuvir, velpatasvir or voxilaprevir Are taking rifampicin
5. Side effects of the drug Vosevi
Common side effects:
Headache, fatigue Nausea, diarrhea Uncommon side effects:
Allergic reactions: difficulty breathing, hives, swelling (face, lips, tongue, throat) Liver damage : right upper abdominal pain, nausea, vomiting, loss of appetite, confusion, fatigue, easy bruising or bleeding, vomiting blood, diarrhea, gastrointestinal bleeding, dark urine, jaundice, yellow eye
6. Notes when using Vosevi
Vosevi treats hepatitis C in certain people with certain genotypes.
If you have a history of hepatitis B , Vosevi can cause it to come back or get worse.
Should have liver function tests regularly
Tell your doctor if you have ever had: hepatitis B, liver diseases other than hepatitis C, kidney disease, diabetes, taking substances blood thinners (warfarin, Coumadin, Jantoven)
During pregnancy, Vosevi should be used only when clearly needed.
Use Vosevi with caution while breastfeeding.
Medicines do not stop the disease from spreading. Do not have unprotected sex, share razors, toothbrushes, share needles
If you have diabetes, your blood sugar may be lower with hepatitis C treatment. May increase Risk of low blood sugar with symptoms: hunger, sudden sweating, tremors, heart palpitations, blurred vision, dizziness, tingling in the hands and feet.
Take an antacid at least 4 hours before or 4 hours after taking Vosevi, as it reduces the absorption of velpatasvir.
Missed dose, overdose and management:
If you miss a dose of Vosevi, take it as soon as possible, skip the missed dose if it is almost time for your next dose. Do not take two doses of Vosevi at the same time.
In the event of an overdose of Vosevi, contact a doctor or emergency room 115 immediately.
7. Vosevi drug interactions
Taking Vosevi with amiodarone can cause dangerous side effects: very slow heartbeat, chest pain, trouble breathing, confusion, memory problems, weakness, fatigue, fainting. May also slow the removal of other drugs from the body including: pitavastatin, rosuvastatin, topotecan.
Drugs that can affect the removal of Vosevi from the body include: atazanavir, cyclosporine, efavirenz, lopinavir, rifamycins, phenobarbital, carbamazepine, phenytoin, primidone
Do not take Vosevi with other products containing sofosbuvir or velpatasvir .
Vosevi is a combination antiviral drug, used to treat chronic hepatitis C. In order for the drug to be effective and safe, it must be used as directed by your doctor. Contact your doctor immediately if you have any questions about Vosevi.
