This is an automatically translated article.
Vortioxetine is an atypical antipsychotic and antidepressant used to treat major depressive disorder (MDD). The drug contains the active ingredient Vortioxetine, which is available in the form of tablets. Follow the article below for more detailed information about the drug Vortioxetine.
1. What is Vortioxetine?
The drug contains the ingredient Vortioxetine with the strength of 5 mg, 10 mg, 20 mg; is prepared in the form of tablets, packed 28 tablets / 2 blisters / box.
Vortioxetine is a serotonin modulator and mimic (a mood enhancer) because it has a multimodal mechanism of action on the serotonin neurotransmitter system, it modulates one or more serotonin receptors and serotonin reuptake inhibitor.
Vortioxetine acts as a serotonin reuptake inhibitor through inhibition of the serotonin transporter, while also acting as an agonist of 5-HT1A, a partial agonist of the 5-HT1B receptor, and antagonist of 5-HT3, 5-HT7, 5-HT1D receptors.
2. What are the effects of vortioxetine?
Vortioxetine is indicated for the treatment of major depressive disorder (MDD) in adults.
Do not use Vortioxetine for humans:
Allergy to vortioxetine or any ingredient of the drug. Have used an MAO inhibitor (eg: isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine) within 14 days. Persons under 18 years old.
3. Dosage and usage of Vortioxetine
3.1. Dosage: Initial dose of Vortioxetine: 10 mg orally once a day Maintenance dose: 5 to 20 mg orally once a day Maximum dose: 20 mg/day Patients who cannot tolerate higher doses can maintain oral 5 mg x 1 time/day. 3.2. How to use Read the instructions for use of Vortioxetine carefully before taking Vortioxetine to be taken by mouth Vortioxetine can be taken with or without food When a dose is missed, take vortioxetine as soon as possible, skip the missed dose if it is almost time. time for the next dose. Do not take two doses of vortioxetine at the same time. If you overdose on vortioxetine, call your doctor right away or go to the nearest medical facility.
4. Vortioxetine side effects
Common side effects: nausea, vomiting, constipation, dizziness ...
Serious side effects:
Allergic reactions: difficulty breathing, hives, swelling in the face, lips, tongue , throat Compulsive thoughts, insomnia, unusual behavior, feeling of extreme happiness or sadness, talking more than usual Anxiety, panic, impulsivity, irritability, trouble sleeping, agitation, hostility hostile, aggressive, restless, hyperactive, depressed Have thoughts of suicide or self-harm. Reduced vision, eye pain, red or swollen eyes Hyponatremia Easy bruising, coughing up blood Memory problems, hallucinations, confusion, slurred speech, weakness Serotonin syndrome: agitation, hallucinations, fever , sweating, shaking, fast heart rate, muscle stiffness, convulsions, loss of coordination, nausea, vomiting, diarrhea
5. Notes when using Vortioxetine
Always be on the lookout for changes in mood and behavior. Report all new or worsening symptoms to your doctor. Tell your doctor if you have ever had: bipolar disorder, a history of drug abuse, suicidal thoughts, glaucoma, seizures, epilepsy, low blood sodium, mental illness, Parkinson's disease, migraine headaches, severe infections. Bipolar disorder and mania should be checked before initiating treatment. Taking vortioxetine during the third trimester of pregnancy can cause withdrawal symptoms, lung problems, or other complications in the baby. Do not start or stop vortioxetine on your own without first consulting your doctor. Withdrawal symptoms may occur if you stop using vortioxetine suddenly. After stopping vortioxetine, wait at least 21 days before starting an MAO inhibitor. Avoid driving or doing dangerous activities as the side effects of vortioxetine can decrease your reaction. Tell your doctor if you are also taking stimulants, opioids, herbal products, or medications for depression.
6. Vortioxetine drug interactions
Drugs that may interact with vortioxetine:
other antidepressants buspirone fentanyl, tramadol lithium St. John's wort, tryptophan (L-tryptophan) warfarin, Coumadin, Jantoven diuretics migraine headache medicine (triptans) NSAIDs (nonsteroidal anti-inflammatory drugs): aspirin, ibuprofen, naproxen, celecoxib, diclofenac, meloxicam epilepsy drugs: carbamazepine , phenytoin. Vortioxetine is used to treat major depressive disorder in adults. When taking the drug, it is necessary to use it exactly as prescribed and strictly follow the doctor's supervision. If you have any questions about Vortioxetine, contact your doctor immediately for advice.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
