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Vnastrole is widely distributed at drugstores nationwide. However, many people still do not understand the use and how to use Vnastrole. The following article will help readers gain more knowledge about drugs.
1. Learn about the drug Vnastrole
Vnastrole is an anti-cancer drug that affects the immune system. Vnastrole medicine contains the main ingredient is Anastrozole 1mg with other active ingredients and excipients. The content of the drug has been fully written on the product packaging or instruction sheet, so you need to read the information carefully before using the drug.
MSN Laboratories Limited is the unit responsible for the production and distribution of Vnastrole in Vietnam, registered with the registration number VN-20073-16. The drug is prepared in the form of film-coated tablets with the form of a box of 3 blisters, each blister of 10 tablets.
2. What effects does Vnastrole have?
The active ingredient Anastrozole in Vnastrole has the ability to selectively inhibit and strongly affect aromatase enzymes of the non-steroidal group. In postmenopausal women, oestradiol is produced primarily from the conversion of androstenedione to oestrone by aromatase complexes in peripheral tissues, after which oestrone is converted to oestradiol. In patients with breast cancer, evidence has shown that reducing the amount of oestradiol in the blood has beneficial effects in these patients. Anastrozole at a dose of 1 mg daily has been shown to reduce oestradiol levels by more than 80% in postmenopausal patients following a highly sensitive test. Anastrozole does not contain estrogenic, androgenic and progesterone-like activity. Administration of Anastrozole doses up to 10 mg daily will not produce any effect on aldosterone or cortisol secretion, as measured before or after standard ACTH stimulation, so no additional corticosteroids are required.At present, Anastrozole cannot be demonstrated whether it increases survival in patients receiving chemotherapy as when using Tamoxifen. The safety of long-term use of Anastrozole has not been established. When used in combination with Anastrozole and Tamoxifen, the effectiveness and safety are similar to when using Tamoxifen monotherapy. The exact mechanism that determines this is currently unknown, but experts do not think this occurs as a result of Anastrozole's reduced ability to inhibit oestradiol.
Each type of pharmaceutical drug will have the main effect to treat a specific disease or condition, so Vnastrole should only be used according to specific indications on the drug's packaging. The drug Vnastrole may be effective for some other diseases not listed, but only if prescribed by a doctor.
3. Indications for the use of Vnastrole
The drug is indicated to support the treatment of postmenopausal women with oestrogen-receptor-positive early-stage breast cancer. The effectiveness of the drug in the treatment of early breast cancer depends on the analysis of recurrence-free survival of patients treated for a median of 31 months.4. Contraindications to the drug Vnastrole
Not for pre-menopausal people; Pregnant and lactating women; Patients with severe renal impairment, moderate to severe liver disease; People who are sensitive to Anastrozole or the active ingredients in the drug If you are being treated with drugs containing oestrogen, you should not use them together because they may lose the pharmacological effect of each other. Children: There are no studies on the effects or complications of this drug in this case, so it should not be used.
5. Dosage and how to use Vnastrole
The drug is produced in tablet form so it will be taken orally. Before use, carefully read the instructions for use printed on the product packaging.
Recommended dosage of Vnastrole:
Adults: Take 1 tablet once a day, 1mg each time; People with mild or moderate renal impairment, people with mild liver disease can keep the same dose.
6. Side effects of Vnastrole
Common side effects (≥ 10%): Hot flashes, usually mild or moderate. Common side effects (1-10%): Pain, stiffness, weakness, vaginal dryness, diarrhea; Uncommon side effects (0.1-1%): Vaginal bleeding, anorexia, hypercholesterolemia, vomiting, somnolence; Rare side effects (<0.01%): Erythema multiforme, Stevens-Johnson syndrome, vaginal bleeding. This is not a complete list of possible side effects. In case of any side effects caused by the drug, the patient should notify the doctor immediately.
The article has provided information about the uses, doses and notes when using Vnastrole. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Vnastrole exactly as directed by your doctor.
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