Uses of Visulin 1g/0.5g

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1. What is Visulin?

Visulin medicine contains 2 main active ingredients, Ampicillin with a strength of 1g and Sulbactam with a content of 0.5g. The drug is prepared in the form of a powder for injection, packed in a box of 10 vials, a box of 1 vial or a box of 1 vial with 1 ampoule of 5ml distilled water for injection.

2. Uses of the drug Visulin

2.1. The effect of the main ingredient in the Visulin 1g/0.5g drug formula is a combination of Ampicillin and Sulbactam with a fixed ratio of 2:1
Active ingredient Ampicillin: This is a semi-synthetic antibiotic with a spectrum of action. wide. Helps inhibit the biosynthesis of mucopeptides of the bacterial cell wall. Active ingredient Sulbactam: Essentially a Penicillanic Sulfonyl Acid, has inhibitory activity on 2 types of Beta - Lactamase mediated by chromosomes and Plasmids. The combined use of these two active ingredients helps:
Create a synergistic effect in killing bacteria. For beta-lactamase bacteria that are resistant to Ampicillin when used alone, this combination helps to extend the antibacterial spectrum of Ampicillin to these species. The spectrum of action: anaerobic bacteria, gram-negative bacteria, gram-positive bacteria. 2.2. Visulin is indicated for use in the following cases:
Respiratory tract infections (upper and lower) including: bacterial pneumonia, sinusitis, epiglottitis, otitis media. Urinary tract infection or inflammation of the kidneys, pyelonephritis. Intra-abdominal infections (cholecystitis, peritonitis,...), gynecological diseases (tubal inflammation, endometritis, pelvic inflammatory disease,...) Bacterial infections on skin, muscles, joints, bone, meningitis, uncomplicated gonococcal infection. Prophylaxis around surgery, indicated for use in patients undergoing abdominal surgery, the pelvis may be contaminated to the peritoneum to help reduce the rate of postoperative infection, or to prevent postpartum infection in case of perioperative infection. cesarean section or termination of pregnancy. 2.3. Contraindications of Visulin Not contraindicated for patients with hypersensitivity to any component of the drug or Penicillin, Cephalosporin. Patients with a history of liver dysfunction or cholestatic jaundice when using 1 or 2, or both active ingredients in Visulin. Contraindicated for patients infected with Herpes Virus, or infectious mononucleosis.

3. Usage and dosage of Visulin

3.1. How to take Visulin The drug is used by deep intramuscular injection, intravenous injection and slow intravenous infusion.
3.2. Dosage of Visulin For adults: The total dose of Sulbactam should not exceed 4g/day.
Mild infections use 1.5 to 3g daily. Moderate infections increased to 6g per day. Severe infections daily increase to 12g, divided into 3 to 4 times a day. For infants, young children, children: Dosage is based on weight, 150mg/kg body weight per day, divided into 3-4 times, especially for infants under 1 week, divided into 2 times a day.
Treatment on gonorrhea, single dose 1.5g combined with oral probenecid 1g.
In patients with renal impairment, dose adjustment and dose interval should be based on the degree of renal impairment, the causative strain and the severity of the infection.
Prophylaxis around surgery using doses from 1.5 to 3g at induction of anesthesia, repeated every 6 to 8 hours/day after surgery.

4. Undesirable effects when using the drug Visulin

The undesirable effects when using Visulin are as follows:
Common symptoms are: diarrhea, rash, pain at the injection site, phlebitis, thrombophlebitis.
Less common symptoms such as: urticaria, malaise, nausea, chest pain, rash, pseudomembranous colitis, glossitis, vomiting, headache, urinary retention, gastritis, erythema multiforme, agranulocytosis, edema, Candida infection, fatigue, flatulence, abdominal distention, anaphylaxis, vaginitis, nephritis, elevated liver enzymes.

5. Insulin drug interactions

Care should be taken when combining treatment with Visulin with the following drugs:
Both active ingredients in Visulin are physico-chemically incompatible with Aminoglycosides and may inactivate this drug. When used together with Probenecid, this active ingredient competitively inhibits the renal tubular elimination of the two active ingredients Ampicillin and Sulbactam. Thereby, increasing and prolonging the concentration of these 2 active ingredients in the serum. Concomitant treatment with Ampicillin and Allopurinol increases the frequency of rash in patients with high uric acid levels. Active ingredient Ampicillin has an effect on the urine glucose test using the copper sulfate method. However, there is no effect when administered by the glucose oxidase method.

6. Pay attention to the use of the drug Visulin

For pregnant women: It is necessary to weigh the benefits of treatment and possible side effects when treated with Visulin on this subject. For nursing mothers: A small amount is excreted in milk. Therefore, breastfeeding should be discontinued when the mother is prescribed Visulin therapy. Visulin is a prescription drug that can cause unwanted effects during use. Therefore, patients do not arbitrarily use but must comply with the prescription of the treating doctor.
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