This is an automatically translated article.
Vincystin 200 is a medicine that reduces the thickness of mucus. The drug is used in the treatment of respiratory diseases with thick mucus, helps clear mucus and increases the effectiveness of the cough reflex.
1. What is Vincystin 200?
Vincystin 200 has the main ingredient is acetylcysteine 200mg, prepared in the form of powder for oral solution. Acetylcysteine (N - acetylcysteine) is an N - acetyl derivative of L - cysteine, which is a natural amino - acid. Acetylcysteine is used as a mucolytic and is used as an antidote when a patient has an overdose of paracetamol. The drug works to reduce the consistency of sputum in the respiratory tract, purulent or not sputum by splitting the disulfide bridge in the mucoprotein of this mucus and facilitating the expulsion of sputum by creating a cough. , postural drainage or by other mechanical means. In addition, Acetylcysteine is also used topically to treat amblyopia. N-Acetylcysteine is used to protect against hepatotoxicity caused by paracetamol overdose, by maintaining or restoring hepatic glutathione levels. Glutathione is required to inactivate the hepatotoxic intermediate metabolite of paracetamol. In paracetamol overdose, a large amount of this metabolite is produced, because the main metabolism of paracetamol is being saturated, so it must be metabolized by another route and create hepatotoxicity. When taking Acetylcysteine, it will convert to cysteine, which stimulates the liver to synthesize glutathione, from which acetylcysteine can protect the liver if treatment is started within 12 hours after paracetamol overdose and treatment should be started as soon as possible.
2. Uses of Vincystin 200
Vincystin 200 is indicated for use in the following cases:
The drug is used to treat mucus in viscous mucus disease (cystic fibrosis of the pancreas). Respiratory pathology with viscous sputum as in acute and chronic bronchitis. Used for routine cleaning in tracheostomy. Used to detoxify paracetamol when necessary Contraindications:
Vincystin 200 is not used in the following cases:
History of bronchial asthma, because taking the drug increases the bronchospasm reflex. Hypersensitivity to the active substance acetylcysteine or to other components of the drug. Children under 2 years old need to be used with caution and under the direction of a doctor.
3. Usage and dosage of Vincystin 200
How to use: Mix the powder with a sufficient amount of water, dissolve the powder and drink. Patients should take the drug after meals to reduce the effect on the stomach.
Dosage:
For cases to help clear mucus:
Adults and children over 7 years old: Take 200 mg and 3 times a day. Children 2-7 years old: Oral 200 mg x 2 times/day. In case as an antidote in the treatment of paracetamol overdose:
The starting dose is high with a dose of 140 mg/kg, followed by once every 4 hours at a dose of 70 mg/kg and a total of about 17 times. Acetylcysteine is most effective when taken within 8 hours of a patient's paracetamol overdose. After this period, the effectiveness will decrease. However, it may be possible to start treatment more than 24 hours later, after which it may still be beneficial. Missed dose and overdose:
Missed dose : If you accidentally forget to take a dose while taking your medicine, take it as soon as you remember. However, if it is almost time for your next dose, you should skip the missed dose. Do not take a double dose to make up for a missed dose. Overdose: An overdose of acetylcysteine has symptoms similar to those of anaphylaxis, but much more severe, especially signs of a drop in blood pressure. Other symptoms include respiratory failure, hemolysis, disseminated intravascular coagulation, and renal failure. Fatalities have also occurred in patients with acetylcysteine overdose during treatment for paracetamol toxicity. An overdose of acetylcysteine can occur when the infusion is too rapid and too high a dose is given. Treatment of overdose of this drug is symptomatic and supportive monitoring.
4. Undesirable effects when using Vincystin 200
Some side effects may be encountered when you take Vincystin 200, including:
Common side effects: Nausea and vomiting. Uncommon: Drowsiness, headache, tinnitus; Stomatitis, more runny nose; Rash, hives. Rare side effects: Bronchospasm accompanied by systemic anaphylactoid reactions; Fever, chills. Other side effects: Flushing, syncope, sweating, joint pain, blurred vision, liver dysfunction, acidosis, convulsions. When experiencing side effects of the drug, you need to stop taking the drug and consult a doctor, if it is severe, you need to be taken to a medical facility immediately for timely emergency treatment.
5. Notes when using Vincystin 200
Vincystin 200 can cause bronchospasm, so it is necessary to be very careful with people with allergies, at risk of asthma flare-ups. Besides, because the drug thins the mucus, it also affects the mucus in the gastrointestinal tract, so it should be used with caution in people with a history of peptic ulcer disease.
When treated with acetylcysteine, a lot of thin sputum may appear in the bronchi. Therefore, you need to aspirate to remove the thin sputum if the patient has a reduced ability to cough.
For pregnant and lactating women: The drug is used to detoxify pregnant women when paracetamol overdose. Currently, the use of the drug has not been found to have an adverse effect on the fetus and is used in lactating women because there is no adverse effect on the nursing infant. Therefore, the drug Vincystin 200 is used for pregnant and lactating women.
Drug interactions: Some drugs can cause interactions when you take Vincystin 200
It is recommended to take tetracycline antibiotics away from the time of taking Acetylcysteine at least 2 hours to avoid drug interactions. Acetylcysteine should not be used concurrently with other cough suppressants, as it can cause severe mucus congestion by impairing the cough reflex. You should consult your doctor before using the combination. Acetylcysteine may potentiate the vasodilator and platelet aggregation inhibitory effects of nitroglycerin. Acetylcysteine is a reducing agent, so it should not be combined with oxidizing agents. Storage: Store the drug in a place with a temperature below 25 degrees Celsius and avoid moisture, avoid direct light. Do not use after expiry date or if the powder shows signs of deterioration.
Vincystin 200 is a medicine that reduces the consistency of mucus. The drug is used in the treatment of respiratory diseases with thick mucus, helping to clear mucus and increase the effectiveness of the cough reflex. Users need to strictly follow the doctor's instructions to achieve the highest effectiveness and avoid unwanted side effects.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
